The average bus between Waltham and St. Louis takes 30h 13m and the fastest bus takes 29h 25m. There is at least one bus per day from Waltham to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Waltham and St. Louis. The earliest departure is at 9:30 AM in the morning, and the last departure from Waltham is at 6:50 PM which arrives into St. Louis at 11:15 PM. All services require a transfer at Lincoln St @ Essex St and take an average of 30h 13m. The schedules shown below are for the next available departures.
Arrives next day


29h 40m • 2 changes
Arrives next day


28h 55m • 2 changes
Arrives next day


29h 40m • 2 changes
Arrives next day


28h 55m • 2 changes
Arrives next day


29h 40m • 2 changes
Arrives next day


28h 25m • 2 changes
Want to know about travelling from Waltham to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Waltham to St. Louis. However, there are services departing from Waltham station and arriving at St. Louis station via New York Midtown. The journey, including transfers, takes approximately 30h 13m.
Waltham to St. Louis bus services, operated by MBTA, depart from Boston station.
Waltham to St. Louis bus services, operated by MBTA, arrive at St Louis Bus Station.
The distance between Waltham and St. Louis is 1,652.7 km. The road distance is 2,053 km.
You can take a bus from Carter St opp Commuter Rail Station to St Louis Bus Station via Lincoln St @ Essex St, Boston, New York Midtown, and Port Authority Bus Terminal in around 30h 5m.