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Orlando to St. Louis buses

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Trip Overview

The average bus between Orlando and St. Louis takes 22h 2m and the fastest bus takes 19h 35m. The bus service runs several times per day from Orlando to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 2m
Duration
998 mi
Distance
$177
Average price
Twice daily
Frequency

Bus

best
  1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus FlixBus N2401 / ...
  2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
19h 45m
$143–280

Orlando to St. Louis bus times

Buses run twice daily between Orlando and St. Louis. The earliest departure is at 12:30 PM in the afternoon, and the last departure from Orlando is at 10:55 PM which arrives into St. Louis at 9:20 PM. All services require a transfer, and take on average 22h 2m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Orlando to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Orlando to St. Louis.ExpandLaunch map view
  • Distance: 998.4 mi
  • Duration: 22h 2m

What companies run services between Orlando, FL, USA and St. Louis, MO, USA?

You can take a bus from Orlando Bus Station to St Louis Bus Station via Atlanta Bus Station in around 19h 45m.

Operators