Rome2Rio

St. Louis to Seattle buses

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Trip Overview

The bus between St. Louis and Seattle takes 46h 10m. There is at least one bus per day from St. Louis to Seattle. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

46h 10m
Duration
2,242 mi
Distance
$470
Average price
Once daily
Frequency

St. Louis to Seattle bus times

Buses run once daily between St. Louis and Seattle. The service departs St. Louis at 11:45 PM at night, which arrives into Seattle at 19:55:00. All services require a transfer, and take on average 46h 10m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USA46h 10m • 1 change

Departing Sunday, November 15, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USA46h 10m • 1 change

Departing Monday, November 16, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USA46h 10m • 1 change

Departing Tuesday, November 17, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USA46h 10m • 1 change

Departing Wednesday, November 18, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USA46h 10m • 1 change

Departing Thursday, November 19, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USA46h 10m • 1 change

Departing Friday, November 20, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USA46h 10m • 1 change

Frequently asked questions

Want to know about travelling from St. Louis to Seattle? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Seattle.ExpandLaunch map view
  • Distance: 2,241.6 mi
  • Duration: 46h 10m

What companies run services between St. Louis, MO, USA and Seattle, WA, USA?

You can take a bus from St Louis Bus Station to Seattle Bus Station via Denver Union Station in around 46h 35m.

Operators