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St. Louis to Des Moines buses

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Trip Overview

The average bus between St. Louis and Des Moines takes 11h 56m and the fastest bus takes 9h 50m. The bus service runs several times per day from St. Louis to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 56m
Duration
442 mi
Distance
$106
Average price
3 times a day
Frequency

Bus via Kansas City

best
  1. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
  2. Take the bus from Kansas City to Des Moinesbus bus Jefferson Lines 804 / ...
8h 25m
$85–141

St. Louis to Des Moines bus times

Buses run 3 times a day between St. Louis and Des Moines. The earliest departure is at 7:40 AM in the morning, and the last departure from St. Louis is at 11:45 PM which arrives into Des Moines at 11:45 AM. All services require a transfer at Kansas City Bus Station and take an average of 11h 56m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from St. Louis to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Des Moines.ExpandLaunch map view
  • Distance: 441.6 mi
  • Duration: 11h 56m

What companies run services between St. Louis, MO, USA and Des Moines, IA, USA?

You can take a bus from St Louis Bus Station to Des Moines via Kansas City Bus Station and Kansas City in around 8h 25m.

Operators