The bus between St. Louis and Des Moines takes 8h 25m. There is at least one bus per day from St. Louis to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between St. Louis and Des Moines. The earliest departure is at 3:20 PM in the afternoon, and the last departure from St. Louis is at 3:20 PM which arrives into Des Moines at 11:45 PM. All services run direct with no transfers required, and take on average 8h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from St. Louis station and arriving at Des Moines station. Services depart once daily, and operate Once daily. The journey takes approximately 8h 25m.
St. Louis to Des Moines bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Book your St. Louis to Des Moines bus tickets online with Greyhound USA.
The distance between St. Louis and Des Moines is 439.8 km. The road distance is 670 km.
Greyhound USA operates a bus from St Louis Bus Station to Des Moines once daily. Tickets cost $65–130 and the journey takes 8h 25m.
