The average bus between St. Louis and Independence takes 9h 17m and the fastest bus takes 5h 23m. The bus service runs several times per day from St. Louis to Independence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between St. Louis and Independence. The earliest departure is at 1:30 AM at night, and the last departure from St. Louis is at 4:30 PM which arrives into Independence at 5:41 AM. All services require a transfer at Kansas City Bus Station and take an average of 9h 17m. The schedules shown below are for the next available departures.

6h 14m • 1 change

7h 1m • 1 change
Arrives next day

13h 11m • 1 change

6h 14m • 1 change

7h 1m • 1 change
Arrives next day

13h 11m • 1 change
Want to know about travelling from St. Louis to Independence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Independence. However, there are services departing from St. Louis station and arriving at Independence station via Kansas City Bus Station station. The journey, including transfers, takes approximately 9h 17m.
St. Louis to Independence bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Independence bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
The distance between St. Louis and Independence is 368.8 km. The road distance is 419 km.
Greyhound USA operates a bus from St Louis Bus Station to Kansas City Bus Station 4 times a day. Tickets cost $40–80 and the journey takes 4h 1m.