The average bus between St. Louis and Boston takes 30h 35m and the fastest bus takes 29h 25m. The bus service runs several times per day from St. Louis to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and Boston. The earliest departure is at 8:45 AM in the morning, and the last departure from St. Louis is at 1:55 PM which arrives into Boston at 9:50 PM. All services require a transfer, and take on average 30h 35m. The schedules shown below are for the next available departures.
Arrives next day

33h • 1 change
Arrives next day

31h 55m • 1 change
Arrives next day

30h 25m • 1 change
Arrives next day

31h 55m • 1 change
Arrives next day

30h 25m • 1 change
Arrives next day

31h 55m • 1 change
Want to know about travelling from St. Louis to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Boston. However, there are services departing from St. Louis station and arriving at Boston station via Newark Penn Station station. The journey, including transfers, takes approximately 30h 35m.
St. Louis to Boston bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Boston bus services, operated by Greyhound USA, arrive at Boston station.
Book your St. Louis to Boston bus tickets online with Greyhound USA and Flixbus USA.
The distance between St. Louis and Boston is 1,666.7 km. The road distance is 2,010 km.
You can take a bus from St Louis Bus Station to Boston via Newark Penn Station in around 30h 10m.