There are 3 ways to get from Rome to Isernia by train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Rome to Isernia by train
Questions & Answers
The cheapest way to get from Rome to Isernia is to bus which costs €8 - €35 and takes 2h 10m.
The fastest way to get from Rome to Isernia is to drive which takes 1h 58m and costs €26 - €40.
Yes, there is a direct bus departing from Roma, Autostazione Tiburtina and arriving at Isernia. Services depart three times a day, and operate every day. The journey takes approximately 2h 10m.
Yes, there is a direct train departing from Roma Termini and arriving at Isernia. Services depart five times a day, and operate every day. The journey takes approximately 2h 8m.
The distance between Rome and Isernia is 186 km. The road distance is 173.1 km.
The best way to get from Rome to Isernia without a car is to train which takes 2h 8m and costs €11 - €17.
The train from Rome Termini to Isernia takes 2h 8m including transfers and departs five times a day.
Rome to Isernia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Roma, Autostazione Tiburtina station.
Rome to Isernia train services, operated by Trenitalia S.p.A., depart from Roma Termini station.
The best way to get from Rome to Isernia is to train which takes 2h 8m and costs €11 - €17. Alternatively, you can bus, which costs €8 - €35 and takes 2h 10m.
What companies run services between Rome, Italy and Isernia, Italy?
Trenitalia S.p.A. operates a train from Roma Termini to Isernia 5 times a day. Tickets cost €11–17 and the journey takes 2h 8m. Alternatively, ATM Azienda di Trasporti Molisana S.p.A. operates a bus from Roma, Autostazione Tiburtina to Isernia 3 times a day. Tickets cost €8–13 and the journey takes 2h 10m. FlixBus also services this route once daily.
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €12–35
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Italy
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More Questions & Answers
Rome to Isernia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Isernia station.
Rome to Isernia train services, operated by Trenitalia S.p.A., arrive at Isernia station.
Yes, the driving distance between Rome to Isernia is 173 km. It takes approximately 1h 58m to drive from Rome to Isernia.
Book your Rome to Isernia bus tickets online with Omio and FlixBus.
There are 422+ hotels available in Isernia.











