Rome2Rio

Rome Termini to Palermo buses

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Trip Overview

The average bus between Rome Termini and Palermo takes 12h 10m and the fastest bus takes 12h 8m. There is at least one bus per day from Rome Termini to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 10m
Duration
956 km
Distance
€54
Average price
Once daily
Frequency

Rome Termini to Palermo bus times

Buses run once daily between Rome Termini and Palermo. The earliest departure is at 7:27 PM in the evening, and the last departure from Rome Termini is at 7:36 PM which arrives into Palermo at 7:45 AM. All services require a transfer at Indipendenza and take an average of 12h 10m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 17m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 15m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 9m • 1 change

Departing Tuesday, November 17, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 9m • 1 change

Departing Wednesday, November 18, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 9m • 1 change

Departing Thursday, November 19, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 9m • 1 change

Departing Friday, November 20, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 9m • 1 change

Departing Saturday, November 21, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàAutoservizi Salemi Srl12h 8m • 1 change

Frequently asked questions

Want to know about travelling from Rome Termini to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome Termini to Palermo.ExpandLaunch map view
  • Distance: 956.4 km
  • Duration: 12h 10m

What companies run services between Rome Termini, Italy and Palermo, Italy?

Autoservizi Salemi Srl operates a bus from Roma, Autostazione Tiburtina to Palermo Terminal Bus twice daily. Tickets cost €35–55 and the journey takes 11h 45m.

Operators