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Port Orange to Key Largo buses

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Trip Overview

The average bus between Port Orange and Key Largo takes 17h 4m and the fastest bus takes 12h 57m. The bus service runs several times per day from Port Orange to Key Largo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 4m
Duration
366 mi
Distance
$73
Average price
Twice daily
Frequency

Port Orange to Key Largo bus times

Buses run twice daily between Port Orange and Key Largo. The earliest departure is at 9:26 AM in the morning, and the last departure from Port Orange is at 8:23 PM which arrives into Key Largo at 9:20 AM. All services require a transfer at Transfer Plaza and take an average of 17h 4m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA18h 55m • 5 changes
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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA12h 57m • 5 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA20h 59m • 5 changes
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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA12h 57m • 5 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA17h 2m • 5 changes
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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA16h 57m • 5 changes

Departing Monday, November 9, 2026

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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA18h 55m • 5 changes
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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA12h 57m • 5 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA18h 55m • 5 changes
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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA15h 57m • 5 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA18h 55m • 5 changes
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    Arrives next day

    VotranVotranFlixbus USAFlixbus USAFlixbus USAGreyhound USA19h 20m • 5 changes

Frequently asked questions

Want to know about travelling from Port Orange to Key Largo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Port Orange to Key Largo.ExpandLaunch map view
  • Distance: 365.7 mi
  • Duration: 17h 4m

What companies run services between Port Orange, FL, USA and Key Largo, FL, USA?

You can take a bus from Church ST. & US 1 Ib to Key Largo Bus Stop via Transfer Plaza, Daytona Beach, Orlando Bus Station, Orlando, and Miami Airport Station in around 12h 30m.

Operators