There are 7 ways to get from Port Orange to Key Largo by taxi, train, bus, bus (Flixbus, Greyhound), car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, train, bus
best- Take the taxi from Port Orange to DeLand
- Take the train from DeLand to Sand Lake Road
- Take the train from Orlando to Miami
- Take the bus from Miami Airport Station to Key Largo Bus Stop
9h 43m$118–358Drive 313.8 mi
cheapest- Drive from Port Orange to Key Largo313.8 mi
5h 18m$58–83Bus
- Take the bus from Daytona Beach to Miami Airport StationFlixBus 2431
- Take the bus from Miami Airport Station to Key Largo Bus StopGreyhound US0720s
12h 40m$63–125Train to Orlando, fly to Miami International Airport, shuttle
- Take the train from DeLand to Sand Lake Road
- Fly from Orlando (MCO) to Miami International Airport (MIA)MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
10h 38m$176–453Train, bus
- Take the train from Deland to Hollywood Amtrak StationSilver Meteor / ...
- Take the bus from Miami Airport Station to Key Largo Bus StopGreyhound US0720s
14h 35m$73–373Bus to Jacksonville, fly to Miami International Airport, shuttle
- Take the bus from Daytona Beach to Jacksonville
- Fly from Jacksonville (JAX) to Miami International Airport (MIA)JAX - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
10h 54m$304–553Train to Orlando, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the train from DeLand to Sand Lake Road
- Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)MCO - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
11h 8m$146–263
Port Orange to Key Largo by bus
Questions & Answers
The cheapest way to get from Port Orange to Key Largo is to drive which costs $55 - $85 and takes 5h 18m.
The fastest way to get from Port Orange to Key Largo is to drive which takes 5h 18m and costs $55 - $85.
No, there is no direct bus from Port Orange to Key Largo. However, there are services departing from Church ST. & US 1 Ib and arriving at Key Largo Bus Stop via Transfer Plaza, Daytona Beach and Miami Airport Station. The journey, including transfers, takes approximately 12h 40m.
The distance between Port Orange and Key Largo is 379 miles. The road distance is 315.7 miles.
The best way to get from Port Orange to Key Largo without a car is to taxi and train and bus which takes 9h 43m and costs $110 - $360.
It takes approximately 9h 43m to get from Port Orange to Key Largo, including transfers.
Port Orange to Key Largo bus services, operated by Flixbus USA, depart from Daytona Beach station.
Port Orange to Key Largo bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Port Orange to Key Largo is 316 miles. It takes approximately 5h 18m to drive from Port Orange to Key Largo.
There are 300+ hotels available in Key Largo.
What companies run services between Port Orange, FL, USA and Key Largo, FL, USA?
You can take a bus from Church ST. & US 1 Ib to Key Largo Bus Stop via Transfer Plaza, Daytona Beach, and Miami Airport Station in around 12h 40m.
- Website
- aa.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $30–220
Flights from Jacksonville to Miami International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $60–390
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $30–220
Flights from Orlando to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $23–160
- Website
- spirit.com
Flights from Orlando to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $35–110
- Phone
- +1 855-724-5411
- info@sunrail.com
- Website
- sunrail.com
Train from DeLand to Sand Lake Road
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- https://sunrail.com
- Phone
- +1 831-539-2901
- guestservices@gobrightline.com
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 34m
- Frequency
- Every 3 hours
- Estimated price
- $15–230
- Book at
- https://www.gobrightline.com
- Smart
- $15–200
- Premium
- $65–230
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Deland to Hollywood Amtrak Station
- Ave. Duration
- 6h 28m
- Frequency
- Twice daily
- Estimated price
- $50–340
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Daytona Beach to Miami Airport Station
- Ave. Duration
- 6h 50m
- Frequency
- 5 times a week
- Estimated price
- $45–100
- Schedules at
- flixbus.com
Bus from Daytona Beach to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $19–26
- Schedules at
- flixbus.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
- Ave. Duration
- 37 min
- Estimated price
- $65–80
Daytona Taxi
- Phone
- +1 386-255-5555
- Website
- daytonataxi.com
American Taxi
- Phone
- +1 386-255-0000
- Website
- facebook.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide










