The average bus between Pisa and Madrid takes 33h 37m and the fastest bus takes 28h 5m. The bus runs, on average, 5 times per week from Pisa to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Pisa and Madrid. The earliest departure is at 6:25 AM in the morning, and the last departure from Pisa is at 11:30 PM which arrives into Madrid at 8:30 AM. All services require a transfer, and take on average 33h 37m. The schedules shown below are for the next available departures.
Want to know about travelling from Pisa to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pisa to Madrid. However, there are services departing from Pisa station and arriving at Madrid station via Genoa. The journey, including transfers, takes approximately 33h 37m.
Pisa to Madrid bus services, operated by FlixBus, depart from Pisa station.
Pisa to Madrid bus services, operated by FlixBus, arrive at Madrid station.
Book your Pisa to Madrid bus tickets online with FlixBus.
The distance between Pisa and Madrid is 1,218.9 km. The road distance is 1,681 km.
You can take a bus from Pisa to Madrid via Genoa in around 25h 5m.