COVID-19 Travel restrictions may apply upon entering France. Learn More.

There are 6 ways to get from Pisa to Lyon by train, bus, night train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  10h 17m

  1. Take the train from Pisa Centrale to Firenze S.M.N. Re
  2. Take the train from Firenze S.M.N. to Torino Porta Susa Fr
  3. Take the train from Torino Porta Susa to Chambery Challes Les Eaux Tgv
  4. Take the train from Chambery Challes Les Eaux to Lyon Part Dieu Ter / ...

116€ - 237€

Cheapest option

Bus  •  11h 50m

  1. Take the bus from PISA - Via Pietrasantina Parcheggio to Milano - Bus Station Lampugnano Baltour
  2. Take the bus from Milan to Lyon Perrache N729 / ...

28€ - 44€

4 alternative options

Bus via Genoa  •  14h 12m

  1. Take the bus from Pisa to Genova Piazza della Vittoria Reggio Calabria
  2. Take the bus from Genoa to Lyon Perrache N719

41€ - 53€

Night train, train  •  14h 37m

  1. Take the night train from Pisa Centrale to Torino Porta Susa Ini
  2. Take the train from Torino Porta Susa to Lyon-Saint Exupery Tgv Tgv

112€ - 142€

Drive  •  6h 23m

  1. Drive from Pisa to Lyon 632.9 km

75€ - 120€

Fly  •  6h 44m

  1. Fly from Pisa (PSA) to Lyon (LYS) PSA - LYS

54€ - 195€

Italy → France
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International entry into France from Italy

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This applies to arrivals from all countries, with no exceptions
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  • Negative COVID-19 test issued at most 3 days before arrival
  • Health screen upon arrival. Those showing symptoms will be asked to self-quarantine
  • Health declaration required
  • Mandatory installation of smart phone app for contact purposes
This applies to arrivals from all countries, with no exceptions
  • 7-day mandatory self-quarantine and COVID-19 test at the end of the isolation period
This applies to arrivals from Australia, Israel, Japan, New Zealand, Singapore, South Korea and United Kingdom
  • Exempted International Movement Certificate for travel required
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Frequently Asked Questions


Yes, but conditions apply when entering France from Italy.

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Domestic travel is restricted

  • Face masks are mandatory
  • There is a social distancing requirement of 1 metre
  • Nationwide control measures in place

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The national COVID-19 helpline number in Lyon is 800 130 000.

Wearing a face mask on public transport in Lyon is mandatory.

The social distance requirement in Lyon is 1 metre.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800 130 000.

No, but conditions apply when returning to Italy from France.

See options for return travel.

Last updated: 4 May 2021
Exceptions may apply, for full details: European Union.

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Questions & Answers

The cost-effective way to get from Pisa to Lyon is to bus, which costs 28€ - 45€ and takes 11h 50m.

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The quickest way to get from Pisa to Lyon is to drive which costs 75€ - 120€ and takes 6h 23m.

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No, there is no direct bus from Pisa to Lyon. However, there are services departing from PISA - Via Pietrasantina Parcheggio and arriving at Lyon Perrache via Milan. The journey, including transfers, takes approximately 11h 50m.

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No, there is no direct train from Pisa to Lyon. However, there are services departing from Pisa Centrale and arriving at Lyon Part Dieu via Firenze S.M.N., Torino Porta Susa and Chambery Challes Les Eaux. The journey, including transfers, takes approximately 10h 17m.

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The distance between Pisa and Lyon is 494 km. The road distance is 632.9 km.

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The best way to get from Pisa to Lyon without a car is to train which takes 10h 17m and costs 110€ - 240€.

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It takes approximately 10h 17m to get from Pisa to Lyon, including transfers.

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Pisa to Lyon bus services, operated by Baltour, depart from PISA - Via Pietrasantina Parcheggio station.

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Pisa to Lyon train services, operated by Trenitalia, depart from Pisa Centrale station.

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The best way to get from Pisa to Lyon is to train which takes 10h 17m and costs 110€ - 240€. Alternatively, you can bus, which costs 28€ - 45€ and takes 11h 50m, you could also fly, which costs 50€ - 200€ and takes 6h 44m.

Mode details

Map of how to get from Pisa to Lyon.
Launch map view
  • Distance: 494 km
  • Duration: 10h 17m

What companies run services between Pisa, Italy and Lyon, France?

You can take a train from Pisa to Lyon via Firenze S.M.N., Torino Porta Susa, and Chambery Challes Les Eaux in around 10h 17m. Alternatively, you can take a bus from Pisa to Lyon via Milan in around 11h 50m.

Airlines
easyJet
Website
easyjet.com
Flights from Pisa to Lyon via London Gatwick
Ave. Duration
10h
When
Friday
Estimated price
65€ - 280€
Flights from Pisa to Lyon via Rome
Ave. Duration
7h
When
Friday
Estimated price
45€ - 210€
Flights from Pisa to Lyon via Marrakech
Ave. Duration
8h 10m
When
Tuesday and Saturday
Estimated price
45€ - 200€
Alitalia
Website
alitalia.com
Flights from Pisa to Lyon via Rome
Ave. Duration
6h 5m
When
Friday
Estimated price
100€ - 290€
KLM
Website
klm.com
Flights from Pisa to Lyon via Amsterdam Schiphol
Ave. Duration
7h 40m
When
Monday, Thursday and Saturday
Estimated price
65€ - 260€
Royal Air Maroc
Website
royalairmaroc.com
Flights from Pisa to Lyon via Casablanca
Ave. Duration
6h 55m
When
Monday and Thursday
Estimated price
160€ - 410€
TAP Portugal
Website
flytap.com
Flights from Pisa to Lyon via Lisbon
Ave. Duration
7h 40m
When
Saturday
Estimated price
40€ - 180€
Train operators
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
Ave. Duration
1h
Frequency
Every 30 minutes
Estimated price
5€ - 12€
Website
Trenitalia
1st Class
10€ - 12€
Trenitalia Frecce

Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.M.N. to Torino Porta Susa
Ave. Duration
2h 49m
Frequency
Every 3 hours
Estimated price
30€ - 100€
Website
Trenitalia Frecce
Super Economy
30€ - 45€
Base Standard
60€ - 80€
Base Premium
70€ - 100€
TGV inOui

France’s high-speed TGV train network runs at speeds of up to 320km/h connecting major cities across France and into neighbouring countries. All TGV tickets include a seat reservation; seating is 1+2 in 1st class, 2+2 in 2nd class. Popular routes include Paris to Marseille and Paris to Strasbourg. Most TGVs have a cafe area, power points at each seat and WiFi.

Contact Details
Phone
0033 892 353535
Website
en.oui.sncf
Train from Torino Porta Susa to Chambery Challes Les Eaux
Ave. Duration
2h 45m
Frequency
3 times a day
Estimated price
40€ - 50€
Website
Oui.SNCF
2nd Class
40€ - 50€
1st Class
40€ - 50€
Train from Torino Porta Susa to Lyon-Saint Exupery Tgv
Ave. Duration
4h 5m
Frequency
Twice a week
Estimated price
55€ - 65€
Website
Oui.SNCF
2nd Class
55€ - 65€
1st Class
55€ - 65€
SNCF

France’s state-owned railway company is a fast and efficient way of travelling around the country, with over 14,000 trains operating daily. SNCF runs the country’s extensive rail network, including the high-speed TGV network, regional TER trains and local Intercités. It also operates international routes including Eurostar and Thalys, as well as the low-cost, long-distance Ouigo services that run on limited routes across France. Book up to 3 months in advance for the cheapest fares. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Chambery Challes Les Eaux to Lyon Part Dieu
Ave. Duration
1h 25m
Frequency
Hourly
Estimated price
17€ - 40€
Website
en.oui.sncf
2nd Class
17€ - 25€
Rail 1st Class
26€ - 40€
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs.

Contact Details
Phone
+41 51 220 11 11
Website
sbb.ch
Train from Chambéry-Challes-les-Eaux to Lyon Part Dieu
Ave. Duration
1h 25m
Frequency
Hourly
Estimated price
40€ - 75€
Website
Swiss Railways (SBB/CFF/FFS)
Trenitalia Intercity Night

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
800 90 60 60
Website
trenitalia.com
Night train from Pisa Centrale to Torino Porta Susa
Ave. Duration
8h 53m
Frequency
Once daily
Estimated price
40€ - 60€
Website
Trenitalia ICN
Schedules at
Trenitalia
Schedules at
Bahn DB
Bus operators
Baltour
Phone
+39 0861 1991900
Email
info@baltour.it
Website
global.flixbus.com
Bus from PISA - Via Pietrasantina Parcheggio to Milano - Bus Station Lampugnano
Ave. Duration
4h 30m
Frequency
Twice daily
Estimated price
13€ - 17€
Website
Baltour
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Milan to Lyon Perrache
Ave. Duration
6h 20m
Frequency
3 times a day
Estimated price
22€ - 27€
Website
flixbus.co.uk
Bus from Genoa to Lyon Perrache
Ave. Duration
10h 30m
Frequency
4 times a week
Estimated price
30€ - 40€
Website
flixbus.co.uk
Blablabus

As the bus subsidiary of French railway SNCF, Ouibus offers eco-friendly coaches serving 35 French cities and 10 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Milan to Lyon - Perrache Bus Station
Ave. Duration
6h 15m
Frequency
Twice daily
Estimated price
15€ - 19€
Website
Blablabus

Want to know more about travelling around France

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There is no direct flight from Pisa Airport to Lyon Airport. The quickest flight takes 6h 5m and has one stopover.

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Pisa to Lyon bus services, operated by FlixBus, arrive at Lyon Perrache station.

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Pisa to Lyon train services, operated by SNCF, arrive at Lyon Part Dieu station.

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Yes, the driving distance between Pisa to Lyon is 633 km. It takes approximately 6h 23m to drive from Pisa to Lyon.

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Air France, Transavia Holland, KLM and six other airlines offer flights from Pisa Airport to Lyon Airport.

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There are 1205+ hotels available in Lyon. Prices start at 75€ per night.

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