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There are 6 ways to get from Pisa to Lyon by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4 h 59 min

  1. Fly from Pisa (PSA) to Lyon (LYS) PSA - LYS

$107 - $422

Cheapest option

Bus via Pisa  •  12 h 44 min

  1. Take the bus from Pisa to Genova
  2. Take the bus from Genova to Turin
  3. Take the bus from Turin to Lyon

$24 - $102

4 alternative options

Train  •  10 h 6 min

  1. Take the train from Pisa C.Le to Firenze Smn Rv / ...
  2. Take the train from Firenze S.Maria Novella to Torino Porta Susa Fr
  3. Take the train from Torino Porta Susa to Lyon Part Dieu Tgv

$116 - $158

Train via Genova Piazza Principe  •  10 h 12 min

  1. Take the train from Pisa Centrale to Genova Piazza Principe Fb / ...
  2. Take the train from Genova Piazza Principe to Torino Porta Nuova Rv / ...
  3. Take the train from Torino Porta Susa to Lyon Part Dieu Tgv

$95 - $132

Bus  •  10 h 55 min

  1. Take the bus from Pisa to Genoa, Genoa 516 / ...
  2. Take the bus from Genoa, Genoa to Turin, Torino 501 / ...
  3. Take the bus from Turin, Torino to Lyon, Lyon Perrache 729

$35 - $61

Drive  •  6 h 27 min

  1. Drive from Pisa to Lyon 399.4 miles

$95 - $140

Questions & Answers

The cheapest way to get from Pisa to Lyon is to bus which costs 30€ - 55€ and takes 10 h 55 min.

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The quickest way to get from Pisa to Lyon is to fly which costs 90€ - 370€ and takes 4 h 59 min.

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No, there is no direct bus from Pisa to Lyon. However, there are services departing from Pisa and arriving at Lyon, Lyon Perrache via Genoa, Genoa and Turin, Torino. The journey, including transfers, takes approximately 10 h 55 min.

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No, there is no direct train from Pisa to Lyon. However, there are services departing from Pisa C.Le and arriving at Lyon Part Dieu via Firenze S.Maria Novella and Torino Porta Susa. The journey, including transfers, takes approximately 10 h 6 min.

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The distance between Pisa and Lyon is 494 km. The road distance is 639.1 km.

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The best way to get from Pisa to Lyon without a car is to train which takes 10 h 6 min and costs 100€ - 140€.

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It takes approximately 4 h 59 min to get from Pisa to Lyon, including transfers.

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Pisa to Lyon bus services, operated by FlixBus, depart from Pisa station.

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Pisa to Lyon train services, operated by Trenitalia, depart from Pisa C.Le station.

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The best way to get from Pisa to Lyon is to fly which takes 4 h 59 min and costs 90€ - 370€. Alternatively, you can train, which costs 100€ - 140€ and takes 10 h 6 min, you could also bus, which costs 30€ - 55€ and takes 10 h 55 min.

Mode details

Map of how to get from Pisa to Lyon.
Launch map view
  • Distance: 308.7 miles
  • Duration: 4 h 59 min

What companies run services between Pisa, Italy and Lyon, France?

Lufthansa, Alitalia and eight other airlines fly from Pisa to Lyon every 3 hours. Alternatively, you can take a train from Pisa to Lyon via Firenze Smn, Firenze S.Maria Novella, Torino Porta Susa, and Torino Porta Susa in around 10 h 6 min.

Airlines
Alitalia
Website
alitalia.com
Flights from Pisa to Lyon via Rome
Ave. Duration
5 h 32 min
When
Monday, Wednesday, Friday, Saturday and Sunday
Estimated price
$100 - $650
Flights from Pisa to Lyon via Rome, Milan Malpensa
Ave. Duration
8 h 20 min
When
Monday to Friday
Estimated price
$290 - $1,200
easyJet
Website
easyjet.com
Flights from Pisa to Lyon via London Gatwick
Ave. Duration
8 h 40 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$80 - $420
Flights from Pisa to Lyon via Rome
Ave. Duration
4 h 25 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$60 - $280
Flights from Pisa to Lyon via Palermo
Ave. Duration
5 h 25 min
When
Tuesday
Estimated price
$80 - $400
KLM
Website
klm.com
Flights from Pisa to Lyon via Amsterdam Schiphol
Ave. Duration
7 h 27 min
When
Wednesday, Friday and Sunday
Estimated price
$65 - $390
Lufthansa
Website
lufthansa.com
Flights from Pisa to Lyon via Munich
Ave. Duration
6 h 40 min
When
Every day
Estimated price
$220 - $900
Vueling Airlines
Website
vueling.com
Flights from Pisa to Lyon via Rome
Ave. Duration
5 h 35 min
When
Friday
Estimated price
$90 - $800
Air France
Website
airfrance.com
Flights from Pisa to Lyon via Paris Orly
Ave. Duration
5 h 40 min
When
Saturday and Sunday
Estimated price
$65 - $320
Train operators
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Pisa C.Le to Firenze Smn
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$6 - $14
Website
orario.trenitalia.com
1st Class
$11 - $14
Train from Genova Piazza Principe to Torino Porta Nuova
Ave. Duration
2 h
Frequency
Hourly
Estimated price
$11 - $26
Website
orario.trenitalia.com
1st Class
$21 - $26
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.Maria Novella to Torino Porta Susa
Ave. Duration
2 h 45 min
Frequency
Every 3 hours
Estimated price
$50 - $75
Website
orario.trenitalia.com
Train from Pisa Centrale to Genova Piazza Principe
Ave. Duration
1 h 53 min
Frequency
Hourly
Estimated price
$23 - $35
Website
orario.trenitalia.com
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Torino Porta Susa to Lyon Part Dieu
Ave. Duration
4 h 17 min
Frequency
4 times a week
Estimated price
$60 - $70
Website
en.oui.sncf
2nd Class
$60 - $70
1st Class
$85 - $120
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Pisa to Genoa, Genoa
Ave. Duration
2 h 15 min
Frequency
Every 4 hours
Estimated price
$9 - $16
Website
flixbus.co.uk
Bus from Genoa, Genoa to Turin, Torino
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$9 - $16
Website
flixbus.co.uk
Bus from Turin, Torino to Lyon, Lyon Perrache
Ave. Duration
4 h 20 min
Frequency
Every 4 hours
Estimated price
$17 - $29
Website
flixbus.co.uk
Lirosi Linee
Phone
0966 57552
Email
info@lirosilinee.com
Website
lirosilinee.com
Bus from Pisa to Genova
Ave. Duration
2 h 40 min
Frequency
6 times a week
Estimated price
$11 - $14
Schedules at
lirosilinee.com
Autolinee Giuliano s.a.s di Giuliano Renato &C.
Phone
+39 0974.836185
Website
giulianobus.com
Bus from Genova to Turin
Ave. Duration
3 h
Frequency
5 times a week
Estimated price
$1 - $3
Schedules at
giulianobus.com
Eurolines FR
Ouibus

As the bus subsidiary of French railway SNCF, Ouibus offers comfortable, eco-friendly coaches serving 35 French cities and 11 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Torino - Bus station to Lyon Gare Perrache
Ave. Duration
5 h 20 min
Frequency
Once a week
Estimated price
$11 - $16
Website
Ouibus
Marino Autolinee
Phone
+39 080 3112335
Email
info@marinobus.it
Website
marinobus.it
Bus from Torino to Lyon
Ave. Duration
5 h 50 min
Frequency
Once a week
Estimated price
$23
Website
Marino Autolinee

Want to know more about travelling around France

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More Questions & Answers

There is no direct flight from Pisa Airport to Lyon Airport. The quickest flight takes 4 h 20 min and has one stopover.

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Pisa to Lyon bus services, operated by FlixBus, arrive at Lyon, Lyon Perrache station.

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Pisa to Lyon train services, operated by inOui TGV, arrive at Lyon Part Dieu station.

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Yes, the driving distance between Pisa to Lyon is 639 km. It takes approximately 6 h 27 min to drive from Pisa to Lyon.

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Ryanair, Vueling Airlines, Air France and six other airlines offer flights from Pisa Airport to Lyon Airport.

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Book your Pisa to Lyon bus tickets online with FlixBus, FlixBus and FlixBus.

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There are 1114+ hotels available in Lyon. Prices start at $62 USD per night.

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