There are 10 ways to get from Pisa to Lyon by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
9h 55m€76–114Bus
cheapest- Take the bus from Pisa to Genoabus 536 / ...
- Take the bus from Genoa to Turinbus 501 / ...
- Take the bus from Turin to Lyonbus 480 / ...
11h 30m€39–72Drive 624.6 km
- Drive from Pisa to Lyoncar 624.6 km
6h 29m€96–139Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Lyon–Saint Exupéry Airport (LYS)plane BLQ - LYS
6h 44m€82–304Train via Turin (Trenitalia)
- Take the train from Pisa Centrale to Genova P.Za Principetrain Fb / ...
- Take the train from Genova P.Za Principe to Torino Lingottotrain
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
10h€45–159Train, bus
- Take the train from Pisa Centrale to Genova P.Za Principetrain Fb / ...
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Lyon - Perrache Bus Stationbus BlaBlaCar Bus
13h 25m€61–154Train, train to Nice Côte D'Azur International Airport, fly
- Take the train from Pisa Centrale to Ventimigliatrain
- Take the train from Ventimiglia to Saint-Laurent-du-Vartrain
- Fly from Nice Côte D'Azur International Airport (NCE) to Lyon–Saint Exupéry Airport (LYS)plane NCE - LYS
9h 17m€117–289Train to Florence Peretola Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Lyon–Saint Exupéry Airport (LYS)plane FLR - LYS
5h 55m€83–236Train, train to Venice Marco Polo Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Venezia Mestretrain
- Fly from Venice Marco Polo Airport (VCE) to Lyon–Saint Exupéry Airport (LYS)plane VCE - LYS
8h 53m€90–289Train, train to Milano Malpensa Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Lyon–Saint Exupéry Airport (LYS)plane MXP - LYS
9h 6m€115–265
Pisa to Lyon by train
Questions & Answers
The cheapest way to get from Pisa to Lyon is to bus which costs €35 - €75 and takes 11h 30m.
The fastest way to get from Pisa to Lyon is to train and fly which takes 5h 55m and costs €80 - €240.
No, there is no direct bus from Pisa to Lyon. However, there are services departing from Pisa and arriving at Lyon via Genoa and Turin. The journey, including transfers, takes approximately 11h 30m.
No, there is no direct train from Pisa to Lyon. However, there are services departing from Pisa Centrale and arriving at Lyon Part Dieu via Florence Santa Maria Novella and Milano Centrale. The journey, including transfers, takes approximately 9h 55m.
The distance between Pisa and Lyon is 826 km. The road distance is 624.6 km.
The best way to get from Pisa to Lyon without a car is to train which takes 9h 55m and costs €75 - €120.
It takes approximately 9h 55m to get from Pisa to Lyon, including transfers.
Pisa to Lyon bus services, operated by FlixBus, depart from Pisa station.
Pisa to Lyon train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Lyon is to train which takes 9h 55m and costs €75 - €120. Alternatively, you can bus, which costs €35 - €75 and takes 11h 30m.
What companies run services between Pisa, Italy and Lyon, France?
You can take a train from Pisa Centrale to Lyon Part Dieu via Florence Santa Maria Novella and Milano Centrale in around 9h 55m. Alternatively, you can take a bus from Pisa to Lyon via Genoa and Turin in around 11h 30m.
- Website
- twinjet.fr
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 30m
- When
- Monday to Friday
- Estimated price
- €380–900
Flights from Milano Malpensa Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h
- When
- Monday to Friday
- Estimated price
- €320–750
- Website
- lufthansa.com
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 42m
- When
- Monday, Wednesday, Thursday, Friday, and Saturday
- Estimated price
- €85–450
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Friday
- Estimated price
- €75–320
- Website
- easyjet.com
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €28–150
- Website
- airfrance.com
Flights from Nice Côte D'Azur International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €29–230
- Website
- volotea.com
Flights from Florence Peretola Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday and Friday
- Estimated price
- €45–170
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Thursday and Sunday
- Estimated price
- €24–150
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 25m
- Frequency
- Every 30 minutes
- Estimated price
- €6–9
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- €25–40
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 4h 1m
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €45–65
- Website
- https://www.italotreno.it/en
- Smart Economy
- €45–65
- Smart Flex
- €50–65
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- €23–45
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 31m
- Frequency
- Once daily
- Estimated price
- €22–45
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Venezia Mestre
- Ave. Duration
- 2h 3m
- Frequency
- Hourly
- Estimated price
- €35–70
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 23m
- Frequency
- Twice a week
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 21m
- Frequency
- Every 4 hours
- Estimated price
- €16–40
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 56m
- Frequency
- 3 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 33m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Ventimiglia to Saint-Laurent-du-Var
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €7–16
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €7–11
- Rail 1st Class
- €11–16
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Milano Centrale to Malpensa Aeroporto T1
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Genoa
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Turin
- Ave. Duration
- 2h 15m
- Frequency
- Every 2 hours
- Estimated price
- €10–18
- Website
- https://www.flixbus.co.uk
Bus from Turin to Lyon
- Ave. Duration
- 4h 10m
- Frequency
- Hourly
- Estimated price
- €18–35
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Genoa - Via Fanti d'Italia Bus Stop to Lyon - Perrache Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- 5 times a week
- Estimated price
- €45–70
- Website
- https://www.blablacar.co.uk/bus
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More Questions & Answers
Pisa to Lyon bus services, operated by FlixBus, arrive at Genoa station.
Pisa to Lyon train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Lyon is 625 km. It takes approximately 6h 29m to drive from Pisa to Lyon.
Book your Pisa to Lyon train tickets online with Omio.
Book your Pisa to Lyon bus tickets online with Omio and FlixBus.
There are 3764+ hotels available in Lyon.












































