There are 6 ways to get from Pisa to Lyon by plane, train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Pisa International Airport (PSA) to Lyon–Saint Exupéry Airport (LYS)plane PSA - LYS
5h 36m€72–227Bus
cheapest- Take the bus from Pisa to Genoabus 536 / ...
- Take the bus from Genoa to Turinbus 501 / ...
- Take the bus from Turin to Lyonbus 480 / ...
11h 17m€43–81Train (Trenitalia)
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
9h 54m€95–202Drive 624.6 km
- Drive from Pisa to Lyoncar 624.6 km
6h 29m€98–142Train via Turin (Trenitalia)
- Take the train from Pisa Centrale to Genova P.Za Principetrain Fb / ...
- Take the train from Genova P.Za Principe to Torino Lingottotrain
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
10h€73–201Train, bus
- Take the train from Pisa Centrale to La Spezia Centraletrain Ic
- Take the bus from La Spezia to Clusesbus
- Take the bus from Cluses 74 to Lyon Part Dieu Gare Routierebus
12h 49m€79–172
Pisa to Lyon by train (Trenitalia)
Questions & Answers
The cheapest way to get from Pisa to Lyon is to bus which costs €40 - €85 and takes 11h 17m.
The fastest way to get from Pisa to Lyon is to fly which takes 5h 36m and costs €70 - €230.
No, there is no direct bus from Pisa to Lyon. However, there are services departing from Pisa and arriving at Lyon via Genoa and Turin. The journey, including transfers, takes approximately 11h 17m.
No, there is no direct train from Pisa to Lyon. However, there are services departing from Pisa Centrale and arriving at Lyon Part Dieu via Firenze S.M.N. and Milano Centrale. The journey, including transfers, takes approximately 9h 54m.
The distance between Pisa and Lyon is 498 km. The road distance is 624.6 km.
The best way to get from Pisa to Lyon without a car is to train which takes 9h 54m and costs €95 - €210.
It takes approximately 5h 36m to get from Pisa to Lyon, including transfers.
Pisa to Lyon bus services, operated by FlixBus, depart from Pisa station.
Pisa to Lyon train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Lyon is to fly which takes 5h 36m and costs €70 - €230. Alternatively, you can train, which costs €95 - €210 and takes 9h 54m, you could also bus, which costs €40 - €85 and takes 11h 17m.
What companies run services between Pisa, Italy and Lyon, France?
Air Dolomiti, Lufthansa, and five other airlines fly from Pisa International Airport (PSA) to Lyon–Saint Exupéry Airport (LYS) 3 times a day. Alternatively, you can take a train from Pisa Centrale to Lyon Part Dieu via Firenze S.M.N. and Milano Centrale in around 9h 54m.
- Website
- lufthansa.com
Flights from Pisa International Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- €140–800
- Website
- airfrance.com
Flights from Pisa International Airport to Lyon–Saint Exupéry Airport via Nantes
- Ave. Duration
- 5h 20m
- When
- Monday and Friday
- Estimated price
- €65–280
- Website
- easyjet.com
Flights from Pisa International Airport to Lyon–Saint Exupéry Airport via Palma Mallorca
- Ave. Duration
- 6h 20m
- When
- Monday and Thursday
- Estimated price
- €55–220
- Website
- brusselsairlines.com
Flights from Pisa International Airport to Lyon–Saint Exupéry Airport via Brussels
- Ave. Duration
- 6h 50m
- When
- Tuesday
- Estimated price
- €55–220
- Website
- volotea.com
Flights from Pisa International Airport to Lyon–Saint Exupéry Airport via Alghero
- Ave. Duration
- 9h
- When
- Friday
- Estimated price
- €50–250
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 25m
- Frequency
- Every 30 minutes
- Estimated price
- €10–17
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- €55–100
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €20–35
- Website
- https://www.trenitalia.com/en.html
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 4h 1m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €9–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €45–85
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- €24–45
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 31m
- Frequency
- Once daily
- Estimated price
- €23–45
- Schedules at
- trenitalia.com
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- €11–21
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 21m
- Frequency
- Every 3 hours
- Estimated price
- €16–40
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 56m
- Frequency
- 3 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 57 min
- Frequency
- Every 4 hours
- Estimated price
- €7–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 23m
- Frequency
- Twice a week
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 8m
- Frequency
- Twice a week
- Estimated price
- €23–65
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–65
- 2nd Class
- €23–35
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Genoa
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- €12–22
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Turin
- Ave. Duration
- 2h 15m
- Frequency
- Every 2 hours
- Estimated price
- €11–20
- Website
- https://www.flixbus.co.uk
Bus from Turin to Lyon
- Ave. Duration
- 4h 10m
- Frequency
- Hourly
- Estimated price
- €21–40
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Turin to Lyon
- Ave. Duration
- 4h 15m
- Frequency
- 5 times a day
- Estimated price
- €20–40
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 0827 34 117
- info@gruppodimaio.it
- Website
- gruppodimaio.it
Bus from La Spezia to Cluses
- Ave. Duration
- 6h 50m
- Frequency
- Twice a week
- Estimated price
- €40–60
- Schedules at
- gruppodimaio.it
- Phone
- 3635
- Website
- sncf-connect.com
Bus from Cluses 74 to Lyon Part Dieu Gare Routiere
- Ave. Duration
- 2h 46m
- Frequency
- Once a week
- Estimated price
- €30–45
- Website
- https://www.sncf-connect.com/en-en
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Italy Travel Guides
Read the travel guide
More Questions & Answers
Pisa to Lyon bus services, operated by FlixBus, arrive at Genoa station.
Pisa to Lyon train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Lyon is 625 km. It takes approximately 6h 29m to drive from Pisa to Lyon.
Book your Pisa to Lyon train tickets online with Omio.
Book your Pisa to Lyon bus tickets online with Omio and FlixBus.
There are 3817+ hotels available in Lyon.


































