There are 10 ways to get from Pisa to Lyon by train (Trenitalia), train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Turin
best- Take the train from Pisa Centrale to Genova P.Za PrincipeFb / ...
- Take the train from Genova P.Za Principe to Torino Lingotto
- Take the train from Torino Porta Susa to Lyon Part DieuFr
9h 43m€76–283Bus
cheapest- Take the bus from Pisa to Florence Villa Constanza Bus Station443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Lyon1501 / ...
13h 15m€36–138Train, bus
- Take the train from Pisa Centrale to Genova P.Za PrincipeFb / ...
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Lyon - Perrache Bus StationBlaBlaCar Bus
13h 14m€44–174Drive 624.5 km
- Drive from Pisa to Lyon624.5 km
6h 26m€96–139Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Bologna Centrale
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Lyon–Saint Exupéry Airport (LYS)BLQ - LYS
6h 40m€99–307Train
- Take the train from Pisa Centrale to Firenze S.M.N.Re
- Take the train from Florence Santa Maria Novella to Milano Centrale
- Take the train from Milano Centrale to Lyon Part DieuFr
9h 55m€92–233Train to Florence Peretola Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Lyon–Saint Exupéry Airport (LYS)FLR - LYS
5h 52m€88–230Train, train to Nice Côte D'Azur International Airport, fly
- Take the train from Pisa Centrale to Genova P.Za Principe
- Take the train from Genova P.Za Principe to Ventimiglia
- Take the train from Ventimiglia to Saint-Laurent-du-Var
- Fly from Nice Côte D'Azur International Airport (NCE) to Lyon–Saint Exupéry Airport (LYS)NCE - LYS
9h 24m€110–302Train, train to Fiumicino International Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.
- Take the train from Florence Santa Maria Novella to Roma Termini
- Fly from Fiumicino International Airport (FCO) to Lyon–Saint Exupéry Airport (LYS)FCO - LYS
8h 24m€97–298Train, train to Venice Marco Polo Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.
- Take the train from Florence Santa Maria Novella to Venezia Mestre
- Fly from Venice Marco Polo Airport (VCE) to Lyon–Saint Exupéry Airport (LYS)VCE - LYS
9h 3m€102–278
Pisa to Lyon by train
Questions & Answers
The cheapest way to get from Pisa to Lyon is to bus which costs €35 - €140 and takes 13h 15m.
The fastest way to get from Pisa to Lyon is to train and fly which takes 5h 52m and costs €85 - €230.
No, there is no direct bus from Pisa to Lyon. However, there are services departing from Pisa and arriving at Lyon via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 13h 15m.
No, there is no direct train from Pisa to Lyon. However, there are services departing from Pisa Centrale and arriving at Lyon Part Dieu via Genova P.Za Principe, Torino Lingotto and Torino Porta Susa. The journey, including transfers, takes approximately 9h 43m.
The distance between Pisa and Lyon is 625 km. The road distance is 624.5 km.
The best way to get from Pisa to Lyon without a car is to train via Turin which takes 9h 43m and costs €75 - €290.
It takes approximately 9h 43m to get from Pisa to Lyon, including transfers.
Pisa to Lyon bus services, operated by FlixBus, depart from Pisa station.
Pisa to Lyon train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
The best way to get from Pisa to Lyon is to train via Turin which takes 9h 43m and costs €75 - €290. Alternatively, you can bus, which costs €35 - €140 and takes 13h 15m.
What companies run services between Pisa, Italy and Lyon, France?
You can take a train from Pisa Centrale to Lyon Part Dieu via Genova P.Za Principe, Torino Lingotto, and Torino Porta Susa in around 9h 43m. Alternatively, you can take a bus from Pisa to Lyon via Florence Villa Constanza Bus Station in around 13h 15m.
- Website
- easyjet.com
Flights from Fiumicino International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- €30–130
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €30–160
- Website
- lufthansa.com
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 55m
- When
- Tuesday and Saturday
- Estimated price
- €80–400
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 40m
- When
- Wednesday, Friday, and Saturday
- Estimated price
- €80–320
- Website
- airfrance.com
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €60–310
Flights from Nice Côte D'Azur International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €30–210
- Website
- volotea.com
Flights from Florence Peretola Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday and Friday
- Estimated price
- €45–170
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Tuesday to Sunday
- Estimated price
- €29–140
- Website
- twinjet.fr
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 30m
- When
- Monday to Friday
- Estimated price
- €370–750
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 1h 54m
- Frequency
- Every 4 hours
- Estimated price
- €17–40
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 33m
- Frequency
- Twice daily
- Estimated price
- €22–55
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 19m
- Frequency
- Every 4 hours
- Estimated price
- €13–21
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 2h 9m
- Frequency
- 3 times a day
- Estimated price
- €12–21
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €13–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 4h 4m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €16–24
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 50m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 2h 41m
- Frequency
- Every 3 hours
- Estimated price
- €9–14
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €23–55
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Venezia Mestre
- Ave. Duration
- 2h 3m
- Frequency
- Every 2 hours
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Ventimiglia to Saint-Laurent-du-Var
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €12
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Genoa - Via Fanti d'Italia Bus Stop to Lyon - Perrache Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- 5 times a week
- Estimated price
- €30–90
- Website
- https://www.blablacar.co.uk/bus
Bus from Florence Villa Constanza Bus Station to Lyon
- Ave. Duration
- 11h
- Frequency
- 6 times a week
- Estimated price
- €28–90
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- €8–18
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Lyon
- Ave. Duration
- 10h 40m
- Frequency
- Twice daily
- Estimated price
- €35–120
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Lyon
- Ave. Duration
- 11h 50m
- Frequency
- Twice daily
- Estimated price
- €30–110
- Website
- https://www.itabus.it/en/home
Want to know more about travelling around France
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More Questions & Answers
Pisa to Lyon bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Lyon train services, operated by Trenitalia Frecce, arrive at Genova P.Za Principe station.
Yes, the driving distance between Pisa to Lyon is 624 km. It takes approximately 6h 26m to drive from Pisa to Lyon.
Book your Pisa to Lyon train tickets online with Omio.
Book your Pisa to Lyon bus tickets online with Omio and FlixBus.
There are 3709+ hotels available in Lyon.








































