Bus Lyon to Avignon from €20 | Tickets & Timetables

Trip Overview

The average bus between Lyon and Avignon takes 3h 43m and the fastest bus takes 2h 56m. The bus service runs several times per day from Lyon to Avignon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 43m
Duration: 230 km
Distance: €20
Average price: Every 4 hours
Frequency

Bus via Le Lac

best

Take the bus from Lyon to Avignonbus FlixBus N1135 / ...

€15–35

Lyon to Avignon bus times

Buses run every 4 hours between Lyon and Avignon. The earliest departure is at 4:40 AM at night, and the last departure from Lyon is at 11:50 PM which arrives into Avignon at 5:59 AM. All services require a transfer, and take on average 3h 43m. The schedules shown below are for the next available departures.

Departing Sunday, May 17, 2026

1:50 PM → 5:33 PM
3h 43m • 1 change
11:50 PM → 6:00 AM
Arrives next day
6h 10m • 1 change

Departing Monday, May 18, 2026

4:40 AM → 7:59 AM
3h 19m • 1 change
5:20 AM → 8:20 AM
3h • 1 change
8:05 AM → 11:29 AM
3h 24m • 1 change
8:30 AM → 11:38 AM
3h 8m • 1 change
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Departing Tuesday, May 19, 2026

4:40 AM → 7:59 AM
3h 19m • 1 change
8:05 AM → 11:29 AM
3h 24m • 1 change
8:30 AM → 11:38 AM
3h 8m • 1 change
11:50 PM → 6:00 AM
Arrives next day
6h 10m • 1 change

Departing Wednesday, May 20, 2026

4:40 AM → 7:59 AM
3h 19m • 1 change
8:05 AM → 11:29 AM
3h 24m • 1 change
8:30 AM → 11:38 AM
3h 8m • 1 change

Departing Thursday, May 21, 2026

4:40 AM → 7:59 AM
3h 19m • 1 change
8:05 AM → 11:29 AM
3h 24m • 1 change
8:30 AM → 11:38 AM
3h 8m • 1 change
9:30 AM → 1:10 PM
3h 40m • 1 change
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Departing Friday, May 22, 2026

4:40 AM → 7:59 AM
3h 19m • 1 change
5:20 AM → 8:20 AM
3h • 1 change
8:05 AM → 11:29 AM
3h 24m • 1 change
8:30 AM → 11:38 AM
3h 8m • 1 change
Show more

Departing Saturday, May 23, 2026

4:40 AM → 8:00 AM
3h 20m • 1 change
5:20 AM → 8:16 AM
2h 56m • 1 change
8:30 AM → 11:35 AM
3h 5m • 1 change
9:30 AM → 1:20 PM
3h 50m • 1 change
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Frequently asked questions

Want to know about travelling from Lyon to Avignon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.