The average bus between Messina and Siena takes 12h 37m and the fastest bus takes 11h 30m. The bus service runs several times per day from Messina to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Messina and Siena. The earliest departure is at 10:55 AM in the morning, and the last departure from Messina is at 8:15 PM which arrives into Siena at 7:45 AM. All services run direct with no transfers required, and take on average 12h 37m. The schedules shown below are for the next available departures.
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Want to know about travelling from Messina to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Messina station and arriving at Siena station. Services depart twice daily, and operate Twice daily. The journey takes approximately 12h 37m.
Messina to Siena bus services, operated by FlixBus, depart from Messina station.
Messina to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Messina to Siena bus tickets online with FlixBus.
The distance between Messina and Siena is 671.4 km. The road distance is 905 km.
FlixBus operates a bus from Messina to Siena twice daily. Tickets cost €60–110 and the journey takes 11h 30m. Itabus S.p.A. also services this route once daily.