There are 9 ways to get from Messina to Siena by car ferry, train, bus, ferry, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Car ferry, train, bus
best- Take the car ferry from Messina Marittima to Villa San Giovannicarferry
- Take the train from Villa San Giovanni to Florence Santa Maria Novellatrain
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
10h 45mTrain to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train
cheapest- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 21m€45–245Bus
- Take the bus from Messina to Sienabus N597 / ...
11h 30m€55–100Ferry, drive
- Take the ferry from Messina Marittima to Villa San Giovanniferry
- Drive from Villa San Giovanni to Sienacar
8h 46m€132–202Train to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 24m€47–167Ferry, train
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Napoli Afragolatrain Fr / ...
- Take the train from Napoli Afragola to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
11h 32mTrain, bus
- Take the train from Messina Centrale to Firenze S.M.N.train 96704
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
14h 28mTrain to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 16m€62–215Train to Palermo Airport, fly to Pisa International Airport, train
- Take the train from Messina Centrale to Palermo Centraletrain
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane PMO - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
9h 13m€72–275
Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Messina to Siena is to bus which costs €55 - €100 and takes 11h 30m.
The fastest way to get from Messina to Siena is to train and fly which takes 7h 16m and costs €60 - €220.
Yes, there is a direct bus departing from Messina and arriving at Siena. Services depart twice daily, and operate every day. The journey takes approximately 11h 30m.
The distance between Messina and Siena is 1004 km.
The best way to get from Messina to Siena without a car is to car ferry and train and bus which takes 10h 45m and costs .
It takes approximately 10h 45m to get from Messina to Siena, including transfers.
Messina to Siena bus services, operated by FlixBus, depart from Messina station.
Messina to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Messina to Siena bus tickets online with Omio and FlixBus.
There are 2301+ hotels available in Siena.
What companies run services between Messina, Italy and Siena, Italy?
FlixBus operates a bus from Messina to Siena twice daily. Tickets cost €55–100 and the journey takes 11h 30m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €40–170
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Malta
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €40–170
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–180
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–190
Flights from Palermo Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- €35–190
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- €70–120
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €50–130
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €21–90
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €28–150
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €26–120
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa San Giovanni to Florence Santa Maria Novella
- Ave. Duration
- 7h 37m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- https://www.italotreno.it/en
- Smart Economy
- €100–140
- Smart Flex
- €110–150
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 48m
- Frequency
- Once daily
- Estimated price
- €60–80
- Website
- https://www.italotreno.it/en
- Smart Economy
- €60–75
- Smart Flex
- €60–80
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €28–40
- Website
- https://www.italotreno.it/en
- Smart Economy
- €28–40
- Smart Flex
- €29–40
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Firenze S.M.N.
- Ave. Duration
- 12h 50m
- Frequency
- Twice a week
- Estimated price
- €45–70
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €13–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- Twice daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- €21–50
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 16m
- Frequency
- Every 4 hours
- Estimated price
- €60–120
- Schedules at
- trenitalia.com
Train from Napoli Afragola to Firenze S.M.N.
- Ave. Duration
- 2h 51m
- Frequency
- Hourly
- Estimated price
- €65–130
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Messina to Siena
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- €55–100
- Website
- https://www.flixbus.co.uk
- Phone
- +39.090.57.37
- servizioclienti@carontetourist.it
- Website
- carontetourist.it
Car ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €2–40
- Schedules at
- carontetourist.it
- Passenger
- €2–7
- Moto
- €16–22
- Car
- €30–40
- Phone
- 3409848540
- info@blujetlines.it
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
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