There are 9 ways to get from Messina to Siena by bus, plane, train, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
best- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)CTA - FLR
- Take the train from Firenze S.M.N. to Siena
6h 45m€51–191Bus
cheapest- Take the bus from Messina to SienaN597 / ...
11h 30m€23–90Train, bus
- Take the train from Messina Centrale to Firenze S.M.N.96502
- Take the bus from Firenze Autostazione to Siena-Via Tozzi131R / ...
12h 55mFerry, drive
- Take the ferry from Messina Marittima to Villa San Giovanni
- Drive from Villa San Giovanni to Siena
8h 42m€132–202Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)CTA - PSA
- Take the train from Pisa Centrale to Empoli
- Take the train from Empoli to Siena
6h 34m€71–209Bus to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Siena
7h 29m€55–268Bus to Catania–Fontanarossa Airport, fly to Perugia Sant'Egidio Airport, bus
- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Perugia Sant'Egidio Airport (PEG)CTA - PEG
- Take the bus from Perugia to Siena
6h 29m€107–425Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus
- Take the train from Messina Centrale to Palermo Centrale
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)PMO - PEG
- Take the bus from Perugia to Siena
9h 8m€113–408Car ferry, bus
- Take the car ferry from Messina Marittima to Villa San Giovanni
- Take the bus from Villa San Giovanni to Firenze Autostazione
- Take the bus from Firenze Autostazione to Siena-Via Tozzi131
14h 53m
Messina to Siena by bus
Questions & Answers
The cheapest way to get from Messina to Siena is to bus which costs €23 - €90 and takes 11h 30m.
The fastest way to get from Messina to Siena is to bus and fly which takes 6h 29m and costs €100 - €430.
Yes, there is a direct bus departing from Messina and arriving at Siena. Services depart twice daily, and operate every day. The journey takes approximately 11h 30m.
The distance between Messina and Siena is 975 km.
The best way to get from Messina to Siena without a car is to bus which takes 11h 30m and costs €23 - €90.
It takes approximately 6h 45m to get from Messina to Siena, including transfers.
Messina to Siena bus services, operated by FlixBus, depart from Messina station.
Messina to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Messina to Siena bus tickets online with Omio, FlixBus and Distribusion.
There are 2186+ hotels available in Siena.
What companies run services between Messina, Italy and Siena, Italy?
FlixBus operates a bus from Messina to Siena twice daily. Tickets cost €35–90 and the journey takes 11h 30m. Itabus S.p.A. also services this route once daily.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €50–160
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Malta
- Ave. Duration
- 3h 40m
- When
- Monday and Thursday
- Estimated price
- €50–160
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €50–150
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 3h 35m
- When
- Tuesday
- Estimated price
- €50–150
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Cagliari
- Ave. Duration
- 4h 10m
- When
- Tuesday
- Estimated price
- €50–150
Flights from Catania–Fontanarossa Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €75–340
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €60–240
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €70–140
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- €50–160
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €22–110
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €26–170
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–200
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Firenze S.M.N.
- Ave. Duration
- 11h 15m
- Frequency
- 3 times a week
- Estimated price
- €45–70
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 51m
- Frequency
- Every 4 hours
- Estimated price
- €13–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–40
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 2m
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €14–35
- Website
- https://www.italotreno.it/en
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €6–9
- Schedules at
- saisautolinee.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Messina to Siena
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- €35–90
- Website
- https://www.flixbus.co.uk
Bus from Perugia to Siena
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €7–14
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Messina to Siena
- Ave. Duration
- 13h 15m
- Frequency
- Once daily
- Estimated price
- €23–35
- Website
- https://www.itabus.it/en/home
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- 0966 57552
- info@lirosiautoservizi.com
- Website
- lirosiautoserviziorari.com
Bus from Villa San Giovanni to Firenze Autostazione
- Ave. Duration
- 11h 30m
- Frequency
- Twice a week
- Estimated price
- €55–65
- Schedules at
- lirosiautoserviziorari.com
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
- Phone
- +39.090.57.37
- servizioclienti@carontetourist.it
- Website
- carontetourist.it
Car ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €2–40
- Schedules at
- carontetourist.it
- Passenger
- €2–7
- Moto
- €16–22
- Car
- €30–40
Want to know more about travelling around Italy
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