There are 9 ways to get from Messina to Siena by ferry, train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry, train via Casoria
best- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
10h 18mTrain, fly to Bologna Guglielmo Marconi Airport
cheapest- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 3m€50–229Bus
- Take the bus from Messina to Sienabus N597 / ...
11h 30m€55–130Ferry, drive
- Take the ferry from Messina Marittima to Villa San Giovanniferry
- Drive from Villa San Giovanni to Sienacar
8h 46m€142–212Train, fly to Florence Peretola Airport
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 24m€64–214Ferry, train (Trenitalia)
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Chiusi-Chianciano T.train Ic
- Take the train from Chiusi-Chianciano T. to Sienatrain Re
12h 43mBus via Florence
- Take the bus from Messina Main Train Station to Florence Villa Constanza Bus Stationbus Itabus
- Take the bus from Stazione Leopolda to Siena-Via Tozzibus 131R / ...
15h 40m€67–127Train, fly to Pisa International Airport
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 21m€63–203Train, fly to Fiumicino International Airport
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)plane CTA - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 7m€78–234
Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Messina to Siena is to bus via Florence which costs €65 - €130 and takes 15h 40m.
The fastest way to get from Messina to Siena is to train and fly which takes 7h 21m and costs €60 - €210.
Yes, there is a direct bus departing from Messina and arriving at Siena. Services depart twice daily, and operate every day. The journey takes approximately 11h 30m.
The distance between Messina and Siena is 993 km.
The best way to get from Messina to Siena without a car is to ferry and train via Casoria which takes 10h 18m and costs .
It takes approximately 10h 18m to get from Messina to Siena, including transfers.
Messina to Siena bus services, operated by FlixBus, depart from Messina station.
Messina to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Messina to Siena bus tickets online with Omio and FlixBus.
There are 2537+ hotels available in Siena.
What companies run services between Messina, Italy and Siena, Italy?
FlixBus operates a bus from Messina to Siena twice daily. Tickets cost €75–130 and the journey takes 11h 30m. Itabus S.p.A. also services this route once daily.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–140
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–170
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Bari
- Ave. Duration
- 3h 45m
- When
- Wednesday
- Estimated price
- €40–170
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 4h 30m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €40–170
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €24–85
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- €80–170
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- €75–180
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €50–100
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €27–150
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €80–170
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €75–180
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- €50–100
- Website
- aeroitalia.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €23–310
- Website
- flexflight.dk
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €23–310
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Friday, and Sunday
- Estimated price
- €50–190
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €17–80
- Website
- neosair.it
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 20m
- When
- Sunday
- Estimated price
- €85–320
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 4m
- Frequency
- Hourly
- Estimated price
- €60–130
- Schedules at
- trenitalia.com
Train from Napoli Afragola to Firenze S.M.N.
- Ave. Duration
- 2h 51m
- Frequency
- Hourly
- Estimated price
- €70–140
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Every 15 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 5h 3m
- Frequency
- Twice daily
- Estimated price
- €50–110
- Website
- https://www.italotreno.it/en
Train from Napoli Afragola to Firenze S.M.N.
- Ave. Duration
- 3h 17m
- Frequency
- 3 times a day
- Estimated price
- €60–120
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 2h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €11–18
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 2h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 2h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 2h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 35m
- Frequency
- Every 3 hours
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- €10–21
- Website
- https://www.trenitalia.com/en.html
Train from Villa S.Giovanni to Chiusi-Chianciano T.
- Ave. Duration
- 9h 25m
- Frequency
- Twice a week
- Estimated price
- €80–170
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- €10–21
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- €10–21
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- €10–21
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Messina to Siena
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- €75–130
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Messina to Siena
- Ave. Duration
- 13h 15m
- Frequency
- Once daily
- Estimated price
- €55–110
- Website
- https://www.itabus.it/en/home
Bus from Messina Main Train Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 13h 40m
- Frequency
- Twice daily
- Estimated price
- €60–120
- Website
- https://www.itabus.it/en/home
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- onebus.it
Bus from Messina Main Train Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 14m
- Frequency
- 3 times a week
- Website
- https://onebus.it/
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Stazione Leopolda to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- 3409848540
- info@blujetlines.it
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
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