The average bus between Messina and Roma Termini takes 10h 33m and the fastest bus takes 9h 49m. The bus service runs several times per day from Messina to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Messina and Roma Termini. The earliest departure is at 1:30 AM at night, and the last departure from Messina is at 9:30 PM which arrives into Roma Termini at 7:22 AM. All services require a transfer, and take on average 10h 33m. The schedules shown below are for the next available departures.

10h 34m • 1 change

10h 56m • 1 change
Arrives next day

9h 49m • 1 change

10h 34m • 1 change

11h 22m • 1 change
Arrives next day

9h 59m • 1 change

10h 34m • 1 change

10h 56m • 1 change
Arrives next day

9h 52m • 1 change

10h 36m • 1 change

11h 4m • 1 change
Arrives next day

9h 52m • 1 change
Want to know about travelling from Messina to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Messina to Roma Termini. However, there are services departing from Messina station and arriving at Roma Termini station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 10h 33m.
Messina to Roma Termini bus services, operated by FlixBus, depart from Messina station.
Messina to Roma Termini bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Messina and Roma Termini is 487.1 km. The road distance is 713 km.
FlixBus operates a bus from Messina to Roma, Autostazione Tiburtina 3 times a day. Tickets cost €50–85 and the journey takes 9h 20m. Autoservizi Salemi also services this route once daily.