The average bus between Melrose Park and Chicago Loop takes 1h 20m and the fastest bus takes 1h 4m. The bus runs at least 2 times per hour from Melrose Park to Chicago Loop. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 30 minutes between Melrose Park and Chicago Loop. The earliest departure is at 5:02 AM in the morning, and the last departure from Melrose Park is at 11:05 PM which arrives into Chicago Loop at 12:16 AM. All services require a transfer at Lake St & Austin Blvd and take an average of 1h 20m. The schedules shown below are for the next available departures.

1h 13m • 1 change

1h 8m • 1 change

1h 13m • 1 change

1h 8m • 1 change
Want to know about travelling from Melrose Park to Chicago Loop? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Melrose Park to Chicago Loop. However, there are services departing from Melrose Park station and arriving at Chicago Loop station via Lake St & Austin Blvd. The journey, including transfers, takes approximately 1h 20m.
Melrose Park to Chicago Loop bus services, operated by Pace Bus, depart from Lake St & 21st Ave station.
Melrose Park to Chicago Loop bus services, operated by Pace Bus, arrive at Washington & Lasalle station.
The distance between Melrose Park and Chicago Loop is 18.6 km. The road distance is 20 km.
You can take a bus from Lake St & 21st Ave to Washington & Lasalle via Lake St & Austin Blvd and Madison & Austin Terminal in around 1h 28m.