The average bus between Ann Arbor and Chicago Loop takes 5h 34m and the fastest bus takes 4h 24m. The bus service runs several times per day from Ann Arbor to Chicago Loop. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Ann Arbor and Chicago Loop. The earliest departure is at 12:35 AM at night, and the last departure from Ann Arbor is at 5:25 PM which arrives into Chicago Loop at 9:42 PM. All services require a transfer at Chicago Bus Station and take an average of 5h 34m. The schedules shown below are for the next available departures.

5h 1m • 1 change

3h 24m • 1 change

5h 15m • 1 change

4h 11m • 1 change

5h 1m • 1 change

3h 24m • 1 change

5h 15m • 1 change

4h 11m • 1 change
Want to know about travelling from Ann Arbor to Chicago Loop? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ann Arbor to Chicago Loop. However, there are services departing from Ann Arbor station and arriving at Chicago Loop station via Chicago Bus Station station. The journey, including transfers, takes approximately 5h 34m.
Ann Arbor to Chicago Loop bus services, operated by Flixbus USA, depart from Ann Arbor station.
Ann Arbor to Chicago Loop bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
The distance between Ann Arbor and Chicago Loop is 324.2 km. The road distance is 396 km.
Greyhound USA operates a bus from Ann Arbor to Chicago Bus Station 3 times a day. Tickets cost $40–80 and the journey takes 5h. Flixbus USA also services this route 5 times a week.