The average bus between Detroit and Chicago Loop takes 7h and the fastest bus takes 5h 24m. The bus service runs several times per day from Detroit to Chicago Loop. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Detroit and Chicago Loop. The earliest departure is at 7:15 AM in the morning, and the last departure from Detroit is at 11:15 PM which arrives into Chicago Loop at 5:56 AM. All services require a transfer at Chicago Bus Station and take an average of 7h. The schedules shown below are for the next available departures.

4h 24m • 1 change

6h 15m • 1 change

7h 9m • 1 change

5h 16m • 1 change

7h 9m • 1 change

5h 16m • 1 change
Arrives next day

6h 21m • 1 change

7h 9m • 1 change

5h 16m • 1 change
Arrives next day

6h 21m • 1 change

4h 24m • 1 change

6h 15m • 1 change

7h 9m • 1 change

5h 16m • 1 change

4h 28m • 1 change

6h 12m • 1 change

7h 6m • 1 change

5h 22m • 1 change
Want to know about travelling from Detroit to Chicago Loop? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Detroit to Chicago Loop. However, there are services departing from Detroit station and arriving at Chicago Loop station via Chicago Bus Station station. The journey, including transfers, takes approximately 7h.
Detroit to Chicago Loop bus services, operated by Greyhound USA, depart from Detroit Bus Station.
Detroit to Chicago Loop bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
The distance between Detroit and Chicago Loop is 381.7 km. The road distance is 463 km.
Greyhound USA operates a bus from Detroit Bus Station to Chicago Bus Station 3 times a day. Tickets cost $45–95 and the journey takes 6h 5m. Flixbus USA also services this route twice daily.