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Mantua to Isernia buses

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Trip Overview

The average bus between Mantua and Isernia takes 12h 41m and the fastest bus takes 11h 55m. The bus runs, on average, 5 times per week from Mantua to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 41m
Duration
642 km
Distance
€64
Average price
5 times a week
Frequency

Mantua to Isernia bus times

Buses run 5 times a week between Mantua and Isernia. The service departs Mantua at 1:30 AM at night, which arrives into Isernia at 13:25:00. All services require a transfer, and take on average 12h 41m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    FlixBusATM Azienda di Trasporti Molisana S.p.A.11h 55m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    FlixBusATM Azienda di Trasporti Molisana S.p.A.11h 55m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    FlixBusFlixBus15h 45m • 1 change

Departing Monday, November 9, 2026

  •  → 

    FlixBusATM Azienda di Trasporti Molisana S.p.A.11h 55m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    FlixBusATM Azienda di Trasporti Molisana S.p.A.11h 55m • 1 change

Frequently asked questions

Want to know about travelling from Mantua to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mantua to Isernia.ExpandLaunch map view
  • Distance: 641.9 km
  • Duration: 12h 41m

What companies run services between Mantua, Italy and Isernia, Italy?

You can take a bus from Mantua to Isernia via Roma, Autostazione Tiburtina in around 8h 45m.

Operators