The average bus between Mainz and Siena takes 20h 20m and the fastest bus takes 18h 20m. The bus runs, on average, 6 times per week from Mainz to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Mainz and Siena. The earliest departure is at 4:00 PM in the afternoon, and the last departure from Mainz is at 8:00 PM which arrives into Siena at 2:20 PM. All services require a transfer at Frankfurt central train station and take an average of 20h 20m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Siena. However, there are services departing from Mainz station and arriving at Siena station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 20h 20m.
Mainz to Siena bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Mainz to Siena bus tickets online with FlixBus.
The distance between Mainz and Siena is 776.8 km. The road distance is 1,155 km.
You can take a bus from Mainz central train station to Siena via Frankfurt central train station and Florence Villa Constanza Bus Station in around 20h 15m.
