Bus Roma Termini to Siena from €25 | Tickets & Timetables

Trip Overview

The average bus between Roma Termini and Siena takes 3h 22m and the fastest bus takes 3h 9m. The bus service runs several times per day from Roma Termini to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 22m
Duration: 237 km
Distance: €25
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Sienabus 1550 / ...

4h 2m

€18–35

Roma Termini to Siena bus times

Buses run every 4 hours between Roma Termini and Siena. The earliest departure is at 5:35 AM in the morning, and the last departure from Roma Termini is at 9:15 PM which arrives into Siena at 12:40 AM. All services require a transfer, and take on average 3h 22m. The schedules shown below are for the next available departures.

Departing Tuesday, June 2, 2026

9:15 PM → 12:40 AM
Arrives next day
3h 24m • 1 change

Departing Wednesday, June 3, 2026

11:31 AM → 3:00 PM
3h 28m • 1 change
1:45 PM → 5:00 PM
3h 14m • 1 change
5:10 PM → 8:24 PM
3h 13m • 1 change
6:28 PM → 9:55 PM
3h 26m • 1 change
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Departing Thursday, June 4, 2026

5:56 AM → 9:15 AM
3h 18m • 1 change
7:15 AM → 10:35 AM
3h 19m • 1 change
7:43 AM → 11:25 AM
3h 41m • 1 change
10:40 AM → 2:20 PM
3h 39m • 1 change
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Departing Friday, June 5, 2026

5:56 AM → 9:15 AM
3h 18m • 1 change
7:15 AM → 10:35 AM
3h 19m • 1 change
7:43 AM → 11:25 AM
3h 41m • 1 change
10:40 AM → 2:20 PM
3h 39m • 1 change
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Departing Saturday, June 6, 2026

5:55 AM → 9:15 AM
3h 19m • 1 change
7:06 AM → 10:35 AM
3h 28m • 1 change
8:02 AM → 11:25 AM
3h 22m • 1 change
11:00 AM → 2:20 PM
3h 20m • 1 change
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Departing Sunday, June 7, 2026

5:55 AM → 9:15 AM
3h 19m • 1 change
7:15 AM → 10:35 AM
3h 19m • 1 change
8:05 AM → 11:25 AM
3h 19m • 1 change
11:00 AM → 2:20 PM
3h 20m • 1 change
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Departing Monday, June 8, 2026

5:35 AM → 9:15 AM
3h 39m • 1 change

Frequently asked questions

Want to know about travelling from Roma Termini to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.