What is the cheapest way to get from Mainz to Siena?

The cheapest way to get from Mainz to Siena is to bus which costs €80 - €150 and takes 20h 11m.

What is the fastest way to get from Mainz to Siena?

The fastest way to get from Mainz to Siena is to fly and bus which takes 6h 4m and costs €130 - €350.

Is there a direct bus between Mainz and Siena?

No, there is no direct bus from Mainz station to Siena. However, there are services departing from Mainz central train station and arriving at Siena via Frankfurt central train station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 20h 11m.

How far is it from Mainz to Siena?

The distance between Mainz and Siena is 824 km. The road distance is 1023.6 km.

How do I travel from Mainz to Siena without a car?

The best way to get from Mainz to Siena without a car is to train and bus which takes 13h 58m and costs €280 - €850.

How long does it take to get from Mainz to Siena?

It takes approximately 6h 4m to get from Mainz to Siena, including transfers.

Where do I catch the Mainz to Siena bus from?

Mainz to Siena bus services, operated by FlixBus, depart from Frankfurt central train station.

Where does the Mainz to Siena bus arrive?

Mainz to Siena bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.

Can I drive from Mainz to Siena?

Yes, the driving distance between Mainz to Siena is 1024 km. It takes approximately 9h 48m to drive from Mainz to Siena.

How do I get a bus ticket from Mainz to Siena?

Book your Mainz to Siena bus tickets online with FlixBus.

Where can I stay near Siena?

There are 2459+ hotels available in Siena.

Mainz to Siena - 8 ways to travel via train, plane, bus, night train, and car

There are 8 ways to get from Mainz to Siena by plane, bus, train, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Florence Peretola Airport, bus
best
1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
2. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus
6h 4m
€132–350
Bus
cheapest
1. Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus N77 / ...
2. Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
20h 11m
€81–142
Train, bus
1. Take the train from Frankfurt to Chiassotrain Ec
2. Take the train from Chiasso to Milano Centraletrain S11
3. Take the train from Milano Centrale to Firenze S.M.N.train Fr
4. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus 131
13h 58m
€280–815
Train, bus via Zurich
1. Take the train from Mainz Hbf to Zürich HBtrain
2. Take the bus from Zürich Bus Station to San Donato Milanesebus 36
3. Take the bus from Milan to Siena Central Train Stationbus
19h 52m
€89–189
Train, night train, bus
1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain 22 / ...
3. Take the night train from Stuttgart Hbf to Verona Porta Nuovanighttrain Nj
4. Take the train from Verona Porta Nuova to Firenze S.M.N.train Fr
5. Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
19h 50m
€105–266
Fly to Bologna Guglielmo Marconi Airport, train, bus
1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
2. Take the train from Bologna Centrale to Firenze S.M.N.train
3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus
6h 28m
€119–358
Fly to Pisa International Airport, train
1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane FRA - PSA
2. Take the train from Pisa Centrale to Empolitrain
3. Take the train from Empoli to Sienatrain
6h 31m
€134–292
Drive 1,023.6 km
1. Drive from Mainz to Sienacar 1,023.6 km
9h 48m
€160–230

Mainz to Siena by train and bus

6Weekly Services

13h 58mAverage Duration

€280Cheapest Price

See schedules

Questions & Answers

Launch map view

Distance: 824.2 km
Duration: 6h 4m

What companies run services between Mainz, Germany and Siena, Italy?

You can take a bus from Mainz central train station to Siena via Frankfurt central train station and Florence Villa Constanza Bus Station in around 20h 11m.

Airlines

Train operators

Bus operators

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