The average bus between Madison and Missouri takes 18h 7m and the fastest bus takes 15h 30m. The bus service runs several times per day from Madison to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Madison and Missouri. The earliest departure is at 5:30 AM in the morning, and the last departure from Madison is at 5:30 PM which arrives into Missouri at 1:35 PM. All services require a transfer at W Jackson Blvd, after S Clinton St and take an average of 18h 7m. The schedules shown below are for the next available departures.


15h 30m • 2 changes
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18h • 2 changes
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20h 5m • 2 changes


15h 30m • 2 changes
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18h • 2 changes
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20h 5m • 2 changes


15h 30m • 2 changes
Arrives next day


18h • 2 changes
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20h 5m • 2 changes
Want to know about travelling from Madison to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madison to Missouri. However, there are services departing from Madison station and arriving at Missouri station via W Jackson Blvd, after S Clinton St. The journey, including transfers, takes approximately 18h 7m.
Madison to Missouri bus services, operated by Vangalder Bus, depart from 250 N. Lake St - Madison UW Campus station.
Madison to Missouri bus services, operated by Vangalder Bus, arrive at Kansas City Bus Station.
Book your Madison to Missouri bus tickets online with Vangalder Bus, Flixbus USA and Greyhound USA.
The distance between Madison and Missouri is 548.1 km. The road distance is 1,162 km.
You can take a bus from 250 N. Lake St - Madison UW Campus to Kansas City Bus Station via W Jackson Blvd, after S Clinton St, Chicago Bus Station, and St Louis Bus Station in around 16h 3m.