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Indianapolis to Missouri buses

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Trip Overview

The average bus between Indianapolis and Missouri takes 12h 6m and the fastest bus takes 8h 50m. The bus service runs several times per day from Indianapolis to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 6m
Duration
489 mi
Distance
$107
Average price
3 times a day
Frequency

Indianapolis to Missouri bus times

Buses run 3 times a day between Indianapolis and Missouri. The earliest departure is at 4:55 AM at night, and the last departure from Indianapolis is at 7:55 PM which arrives into Missouri at 3:45 AM. All services require a transfer, and take on average 12h 6m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USA8h 50m • 1 change

Departing Monday, November 9, 2026

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    Greyhound USAGreyhound USA15h 50m • 1 change
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    Greyhound USAGreyhound USA11h 40m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA8h 50m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Greyhound USAGreyhound USA15h 50m • 1 change
  •  → 

    Greyhound USAGreyhound USA11h 40m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA8h 50m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Greyhound USAGreyhound USA15h 50m • 1 change
  •  → 

    Greyhound USAGreyhound USA11h 40m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA8h 50m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Greyhound USAGreyhound USA15h 50m • 1 change
  •  → 

    Greyhound USAGreyhound USA11h 40m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA8h 50m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Greyhound USAGreyhound USA15h 50m • 1 change
  •  → 

    Greyhound USAGreyhound USA11h 40m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA8h 50m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Greyhound USAGreyhound USA15h 50m • 1 change
  •  → 

    Greyhound USAGreyhound USA11h 40m • 1 change

Frequently asked questions

Want to know about travelling from Indianapolis to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Indianapolis to Missouri.ExpandLaunch map view
  • Distance: 489.3 mi
  • Duration: 12h 6m

What companies run services between Indianapolis, IN, USA and Missouri, USA?

You can take a bus from Indianapolis Union Station to Kansas City Bus Station via St Louis Bus Station in around 8h 55m.

Operators