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How to get fromMadison to Missouriby bus, plane, train, bus (Flixbus, Greyhound), or car

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There are 10 ways to get from Madison to Missouri by bus, plane, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to General Mitchell International Airport, fly to Lambert–St. Louis International Airport

    best
    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    5h 3m
    $144–922

  2. Drive 466.5 mi

    cheapest
    1. Drive from Madison to Kansas Citycar car 466.5 mi
    8h 15m
    $86–123

  3. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    12h 35m
    $146–326

  4. Bus

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    16h 2m
    $101–201

  5. Bus to Chicago O'Hare International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    5h 59m
    $297–653

  6. Bus to Chicago O'Hare International Airport, fly to Columbia Regional Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane plane ORD - COU
    5h 49m
    $119–415

  7. Bus to Chicago O'Hare International Airport, fly to Springfield-Branson National Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)plane plane ORD - SGF
    5h 59m
    $90–390

  8. Bus to General Mitchell International Airport, fly to Kansas City

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Kansas City (MCI)plane plane MKE - MCI
    6h 10m
    $171–1,019

  9. Bus to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    7h 18m
    $131–813

  10. Bus, train via Milwaukee

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Napervilletrain train
    4. Take the train from Naperville Amtrak Station to Kansas Citytrain train
    13h 29m
    $160–334

Madison to Missouri by bus, train, and tram

Calendar14Weekly Services
Duration12h 35mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Madison to Missouri.ExpandLaunch map view
  • Distance: 418.3 mi
  • Duration: 5h 3m

What companies run services between Madison, WI, USA and Missouri, USA?

You can take a bus from 250 N. Lake St - Madison UW Campus to Kansas City Bus Station via W Jackson Blvd, after S Clinton St, Chicago Bus Station, and St Louis Bus Station in around 16h 2m.

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