The average bus between Lille and Siena takes 22h 36m and the fastest bus takes 21h 50m. There is at least one bus per day from Lille to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Lille and Siena. The earliest departure is at 2:35 PM in the afternoon, and the last departure from Lille is at 9:05 PM which arrives into Siena at 6:55 PM. All services require a transfer at Paris - Bercy-Seine Bus Station and take an average of 22h 36m. The schedules shown below are for the next available departures.
Arrives next day


23h 45m • 2 changes
Arrives next day


21h 50m • 2 changes
Arrives next day


23h 45m • 2 changes
Arrives next day


21h 50m • 2 changes
Want to know about travelling from Lille to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lille to Siena. However, there are services departing from Lille station and arriving at Siena station via Paris - Bercy-Seine Bus Station station. The journey, including transfers, takes approximately 22h 36m.
Lille to Siena bus services, operated by BlaBlaCar Bus, depart from Lille - Europe Train Station.
Lille to Siena bus services, operated by BlaBlaCar Bus, arrive at Siena station.
Book your Lille to Siena bus tickets online with BlaBlaCar Bus and FlixBus.
The distance between Lille and Siena is 1,026 km. The road distance is 1,497 km.
You can take a bus from Lille - Europe Train Station to Siena via Paris - Bercy-Seine Bus Station and Florence Villa Constanza Bus Station in around 23h.