There are 11 ways to get from Lille to Siena by train, plane, train (TGV, Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Brussels Airport, fly to Florence Peretola Airport, train
best- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane BRU - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 8m€101–298Train, bus to Beauvais–Tillé Airport, fly to Pisa International Airport
cheapest- Take the train from Lille Flandres to Amienstrain
- Take the bus from Gare routiere to Aéroportbus
- Fly from Beauvais–Tillé Airport (BVA) to Pisa International Airport (PSA)plane BVA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
9h 8m€75–234Train
- Take the train from Lille Flandres to Chambery Challes Les Eauxtrain Tgv
- Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
13h 53m€236–407Bus
- Take the bus from Lille to Brussels-North train stationbus 228 / ...
- Take the bus from Bruxelles - Rue du Progrès to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
21h 43m€165–243Drive 1,281 km
- Drive from Lille to Sienacar 1,281 km
13h 55m€207–299Train to Paris Charles De Gaulle Airport, fly to Florence Peretola Airport, train
- Take the train from Lille Europe to Aeroport Cdg2 Tgv Roissytrain
- Fly from Paris Charles De Gaulle Airport (CDG) to Florence Peretola Airport (FLR)plane CDG - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 2m€139–338Train to Brussels Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Bologna Guglielmo Marconi Airport (BLQ)plane BRU - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
7h 28m€108–348Train to Brussels South Charleroi Airport, fly to Pisa International Airport, train
- Take the train from Lille Flandres to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane CRL - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
8h 1m€76–270Train to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Lille Flandres to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)plane CRL - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 38m€89–292Train to Brussels Airport, fly to Milan Linate Airport, train
- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Milan Linate Airport (LIN)plane BRU - LIN
- Take the train from Milano Rogoredo to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 1m€101–371Bus via Paris
- Take the bus from Lille to Parisbus 822 / ...
- Take the bus from Paris to Florencebus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
22h 10m€122–185
Lille to Siena by train
Comparing Your Travel Options
The cheapest way to get from Lille to Siena is to train and fly which costs €75 - €270 and takes 8h 1m.
The fastest way to get from Lille to Siena is to train and fly which takes 7h 2m and costs €130 - €340.
No, there is no direct bus from Lille to Siena. However, there are services departing from Lille and arriving at Siena via Bruxelles - Rue du Progrès and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 21h 43m.
No, there is no direct train from Lille to Siena. However, there are services departing from Lille Flandres and arriving at Siena via Chambery Challes Les Eaux, Torino Porta Susa and Firenze S.M.N.. The journey, including transfers, takes approximately 13h 53m.
The distance between Lille and Siena is 1156 km. The road distance is 1281 km.
The best way to get from Lille to Siena without a car is to train which takes 13h 53m and costs €230 - €410.
It takes approximately 7h 8m to get from Lille to Siena, including transfers.
Lille to Siena bus services, operated by FlixBus, depart from Lille station.
Lille to Siena train services, operated by TGV inOui, depart from Lille Flandres station.
The best way to get from Lille to Siena is to train which takes 13h 53m and costs €230 - €410. Alternatively, you can bus, which costs €160 - €250 and takes 21h 43m.
What companies run services between Lille, France and Siena, Italy?
You can take a train from Lille Flandres to Siena via Chambery Challes Les Eaux, Torino Porta Susa, and Firenze S.M.N. in around 13h 53m. Alternatively, you can take a bus from Lille to Siena via Brussels-North train station, Bruxelles - Rue du Progrès, and Florence Villa Constanza Bus Station in around 21h 43m.
- Website
- lufthansa.com
Flights from Brussels Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €90–370
Flights from Brussels Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 25m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–360
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €190–650
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €75–400
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €60–240
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- €140–480
Flights from Brussels Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €140–470
- Website
- ryanair.com
Flights from Brussels South Charleroi Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–210
Flights from Brussels South Charleroi Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €40–220
Flights from Beauvais–Tillé Airport to Pisa International Airport
- Ave. Duration
- 1h 45m
- When
- Friday, Sunday, Monday, Wednesday, Thursday, and Saturday
- Estimated price
- €35–170
- Website
- klm.com
Flights from Brussels Airport to Florence Peretola Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- €65–370
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- €60–370
Flights from Brussels Airport to Milan Linate Airport via Amsterdam Schiphol
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €50–310
- Website
- brusselsairlines.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €90–210
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €60–200
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €75–290
- Website
- airfrance.com
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- €60–370
- Website
- ita-airways.com
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €60–200
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €75–290
- Website
- swiss.com
Flights from Brussels Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- €75–370
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €85–260
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €60–200
- Website
- easyjet.com
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- €30–150
- Website
- vueling.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 55m
- When
- Thursday and Sunday
- Estimated price
- €50–200
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 33 min
- Frequency
- Hourly
- Estimated price
- €21–35
- Website
- TGV inOui
Train from Lille Flandres to Chambery Challes Les Eaux
- Ave. Duration
- 4h 51m
- Frequency
- Twice a week
- Estimated price
- €150–230
- Website
- TGV inOui
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 37m
- Frequency
- Every 4 hours
- Estimated price
- €40–60
- Website
- TGV inOui
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- €40–60
- Website
- TGV inOui
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 33 min
- Frequency
- Hourly
- Estimated price
- €21–35
- Website
- TGV inOui
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 33 min
- Frequency
- Hourly
- Estimated price
- €21–35
- Website
- TGV inOui
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Eurostar
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Eurostar
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Eurostar
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 34m
- Frequency
- 4 times a day
- Estimated price
- €23–35
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- €60–110
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 1h 46m
- Frequency
- Hourly
- Estimated price
- €40–70
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h 23m
- Frequency
- Once daily
- Estimated price
- €50–90
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 59 min
- Frequency
- 3 times a day
- Estimated price
- €35–55
- Website
- Belgian Railways
Train from Lille Flandres to Charleroi-Central
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €20–35
- Website
- Belgian Railways
Train from Lille Flandres to Charleroi-Central
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €20–35
- Website
- Belgian Railways
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- €35–60
- Website
- Oui.SNCF
Train from Lille Flandres to Amiens
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €22–40
- Website
- Oui.SNCF
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 3h 22m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Lille to Brussels-North train station
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- €9–15
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Lille to Paris
- Ave. Duration
- 2h 35m
- Frequency
- Every 3 hours
- Estimated price
- €19–30
- Website
- Flixbus
Bus from Paris to Florence
- Ave. Duration
- 16h 50m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Bruxelles - Rue du Progrès to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 6m
- Frequency
- Once a week
- Estimated price
- €150–220
- Website
- Onebus
- Phone
- 09 70 15 01 50
- contact@oise-mobilite.fr
- Website
- Oise - Réseau de l'Oise
Bus from Gare routiere to Aéroport
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- €1
- Website
- Oise - Réseau de l'Oise
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Lille to Paris
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- €17–28
- Website
- BlaBlaCar Bus
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
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Booking & Getting There
Lille to Siena bus services, operated by FlixBus, arrive at Brussels-North train station.
Lille to Siena train services, operated by TGV inOui, arrive at Chambery Challes Les Eaux station.
Yes, the driving distance between Lille to Siena is 1281 km. It takes approximately 13h 55m to drive from Lille to Siena.
Book your Lille to Siena train tickets online with Omio.
Book your Lille to Siena bus tickets online with Omio.
There are 1773+ hotels available in Siena.
























































