There are 12 ways to get from Lille to Siena by train, plane, bus, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Brussels Airport, fly to Florence Peretola Airport, train
best- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane BRU - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 29m€97–271Bus
cheapest- Take the bus from Lille - Europe Train Station to Paris - Bercy-Seine Bus Stationbus
- Take the bus from Paris - Bercy-Seine Bus Station to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
21h 57m€74–162Train, bus via Milan
- Take the train from Lille Europe to Aeroport Cdg2 Tgv Roissytrain Tgv
- Take the train from Aeroport Cdg2 Tgv Roissy to Milano P.Garibalditrain Tgv
- Take the train from Milano Rogoredo to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
13h 37mDrive 1,285.2 km
- Drive from Lille to Sienacar 1,285.2 km
13h 45m€200–288Train to Paris Charles De Gaulle Airport, fly to Florence Peretola Airport, train
- Take the train from Lille Europe to Aeroport Cdg2 Tgv Roissytrain
- Fly from Paris Charles De Gaulle Airport (CDG) to Florence Peretola Airport (FLR)plane CDG - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 20m€113–326Train to Brussels Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Bologna Guglielmo Marconi Airport (BLQ)plane BRU - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
8h 10m€111–323Train to Brussels South Charleroi Airport, fly to Pisa International Airport, train
- Take the train from Lille Flandres to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane CRL - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
8h 27m€81–211Train to Paris Orly Airport, fly to Florence Peretola Airport, train
- Take the train from Lille Flandres to Paris Nordtrain
- Fly from Paris Orly Airport (ORY) to Florence Peretola Airport (FLR)plane ORY - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 6m€116–330Train to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Lille Flandres to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)plane CRL - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
9h 36m€98–276Train to Brussels Airport, fly to Milan Linate Airport, train
- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Milan Linate Airport (LIN)plane BRU - LIN
- Take the train from Milano Rogoredo to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 25m€92–344Train, bus
- Take the train from Lille Flandres to Gand-Dampoorttrain Ic
- Take the bus from Gent to Bolognabus
- Take the bus from Bologna Centrale to Siena Central Train Stationbus
23h 46mDrive, car train
- Drive from Lille to Düsseldorf Hbfcar
- Take the car train from Düsseldorf Hbf to Villach Hbfcartrain
- Drive from Villach Hbf to Sienacar
14h 53m€232–1,199
Brussels Airport (BRU) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Lille to Siena is to bus which costs €70 - €170 and takes 21h 57m.
The fastest way to get from Lille to Siena is to train and fly which takes 7h 20m and costs €110 - €330.
No, there is no direct bus from Lille station to Siena. However, there are services departing from Lille - Europe Train Station and arriving at Siena via Paris - Bercy-Seine Bus Station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 21h 57m.
The distance between Lille and Siena is 1156 km. The road distance is 1285.2 km.
The best way to get from Lille to Siena without a car is to train and bus via Milan which takes 13h 37m and costs .
It takes approximately 7h 29m to get from Lille to Siena, including transfers.
Lille to Siena bus services, operated by BlaBlaCar Bus, depart from Lille - Europe Train Station.
Lille to Siena bus services, operated by BlaBlaCar Bus, arrive at Paris - Bercy-Seine Bus Station.
Yes, the driving distance between Lille to Siena is 1285 km. It takes approximately 13h 45m to drive from Lille to Siena.
Book your Lille to Siena bus tickets online with Omio.
What companies run services between Lille, France and Siena, Italy?
You can take a bus from Lille - Europe Train Station to Siena via Paris - Bercy-Seine Bus Station and Florence Villa Constanza Bus Station in around 21h 57m.
- Website
- lufthansa.com
Flights from Brussels Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €70–240
Flights from Brussels Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 5m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–420
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €100–340
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- €65–230
Flights from Brussels Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €75–340
- Website
- brusselsairlines.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- €130–200
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Friday, and Sunday
- Estimated price
- €65–190
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- €50–260
- Website
- klm.com
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- €60–350
Flights from Brussels Airport to Milan Linate Airport via Amsterdam Schiphol
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €50–300
- Website
- ryanair.com
Flights from Brussels South Charleroi Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–190
Flights from Brussels South Charleroi Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €50–200
- Website
- ita-airways.com
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Friday, and Sunday
- Estimated price
- €65–190
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- €50–260
- Website
- airfrance.com
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- €60–350
- Website
- vueling.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 45m
- When
- Thursday and Sunday
- Estimated price
- €45–170
Flights from Paris Orly Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €50–210
- Website
- swiss.com
Flights from Brussels Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €75–240
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €80–300
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 4h 10m
- When
- Tuesday and Wednesday
- Estimated price
- €65–190
- Website
- easyjet.com
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- €30–130
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 34 min
- Frequency
- Every 2 hours
- Estimated price
- €15–30
- Website
- https://www.sncf-connect.com/en-en
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- €25–70
- Website
- https://www.sncf-connect.com/en-en
Train from Aeroport Cdg2 Tgv Roissy to Milano P.Garibaldi
- Ave. Duration
- 7h 20m
- Frequency
- Twice a week
- Estimated price
- €110–260
- Website
- https://www.sncf-connect.com/en-en
Train from Lille Flandres to Paris Nord
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €30–70
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 37 min
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- https://www.eurostar.com/rw-en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 1h 6m
- Frequency
- 3 times a day
- Estimated price
- €30–75
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €30–50
- Rail 1st Class
- €50–75
Train from Lille Flandres to Paris Nord
- Ave. Duration
- 2h 19m
- Frequency
- 4 times a week
- Estimated price
- €43–45
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 3h 18m
- Frequency
- Once daily
- Estimated price
- €65–120
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €80–120
- 2nd Class
- €65–90
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- €25–55
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.italotreno.it/en
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Lille Flandres to Charleroi-Central
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €11–17
- 1st Class
- €18–26
Train from Lille Flandres to Gand-Dampoort
- Ave. Duration
- 1h 26m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €8–13
- 1st Class
- €13–19
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Düsseldorf Hbf to Villach Hbf
- Ave. Duration
- 5h 53m
- Frequency
- Once a week
- Estimated price
- €100–1,000
- Website
- https://urlaubs-express.de/?lang=en
- Car Single Bed
- €270–550
- Car Compartment
- €550–1,000
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Lille - Europe Train Station to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- €8–25
- Website
- https://www.blablacar.co.uk/bus
Bus from Paris - Bercy-Seine Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 35m
- Frequency
- 6 times a week
- Estimated price
- €60–120
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lille - Europe Train Station to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- 6 times a week
- Estimated price
- €9–26
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–16
- Website
- https://www.flixbus.co.uk
Bus from Bologna Centrale to Siena Central Train Station
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- €6–19
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- €6–16
- Website
- https://www.itabus.it/en/home
Bus from Bologna Centrale to Siena Central Train Station
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- €7–40
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–13
- Website
- https://marinobus.it/en/
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Gent to Bologna
- Ave. Duration
- 18h
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
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