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How to get fromLille to Sienaby train, plane, train (Eurostar), bus, car or car train

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There are 12 ways to get from Lille to Siena by train, plane, train (Eurostar), bus, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Brussels Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
    2. Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)planeBRU - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 36m
    €89–270

  2. Train to Brussels South Charleroi Airport, fly to Pisa International Airport, train

    cheapest
    1. Take the train from Lille Flandres to Charleroi-Centraltrain
    2. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)planeCRL - PSA
    3. Take the train from Pisa Centrale to Empolitrain
    4. Take the train from Empoli to Sienatrain
    8h 30m
    €70–221

  3. Train

    1. Take the train from Lille Europe to Chambery Challes Les Eauxtrain
    2. Take the train from Chambery Challes Les Eaux to Milano CentraletrainFr
    3. Take the train from Milano Centrale to Florence Santa Maria Novellatrain
    4. Take the train from Firenze S.M.N. to SienatrainRe
    13h 30m
    €239–519

  4. Bus

    1. Take the bus from Lille - Europe Train Station to Paris - Bercy-Seine Bus Stationbus
    2. Take the bus from Paris - Bercy-Seine Bus Station to Florence Villa Constanza Bus Stationbus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus443 / ...
    21h 57m
    €80–176

  5. Drive 1,280.7 km

    1. Drive from Lille to Sienacar1,280.7 km
    13h 45m
    €197–284

  6. Train to Paris Charles De Gaulle Airport, fly to Florence Peretola Airport, train

    1. Take the train from Lille Europe to Aeroport Cdg2 Tgv Roissytrain
    2. Fly from Paris Charles De Gaulle Airport (CDG) to Florence Peretola Airport (FLR)planeCDG - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 24m
    €109–315

  7. Train to Paris Orly Airport, fly to Florence Peretola Airport, train

    1. Take the train from Lille Flandres to Paris Nordtrain
    2. Fly from Paris Orly Airport (ORY) to Florence Peretola Airport (FLR)planeORY - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    8h 14m
    €112–330

  8. Train to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Lille Flandres to Charleroi-Centraltrain
    2. Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)planeCRL - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train
    4. Take the train from Firenze S.M.N. to Sienatrain
    9h 30m
    €86–290

  9. Train, bus to Beauvais–Tillé Airport, fly to Pisa International Airport

    1. Take the train from Lille Flandres to Amienstrain
    2. Take the bus from Gare routière to Aéroportbus
    3. Fly from Beauvais–Tillé Airport (BVA) to Pisa International Airport (PSA)planeBVA - PSA
    4. Take the train from Pisa Centrale to Empolitrain
    5. Take the train from Empoli to Sienatrain
    9h 49m
    €110–306

  10. Train, bus via Milan

    1. Take the train from Lille Europe to Aeroport Cdg2 Tgv RoissytrainTgv
    2. Take the train from Aeroport Cdg2 Tgv Roissy to Milano P.GaribalditrainTgv
    3. Take the train from Milano Rogoredo to Firenze S.M.N.trainFr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131
    13h 34m

  11. Train, bus

    1. Take the train from Lille Flandres to Gand-DampoorttrainIc / ...
    2. Take the bus from Gent to Bolognabus
    3. Take the bus from Bologna Centrale to Siena Central Train Stationbus
    23h 46m

  12. Drive, car train

    1. Drive from Lille to Düsseldorf Hbfcar
    2. Take the car train from Düsseldorf Hbf to Villach Hbfcartrain
    3. Drive from Villach Hbf to Sienacar
    14h 50m
    €232–1,198

Lille to Siena by train

Calendar1Weekly Trains
Duration13h 30mAverage Duration
Ticket€239Cheapest Price
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Questions & Answers

What companies run services between Lille, France and Siena, Italy?

You can take a train from Lille Europe to Siena via Chambery Challes Les Eaux, Milano Centrale, and Firenze S.M.N. in around 13h 30m. Alternatively, you can take a bus from Lille - Europe Train Station to Siena via Paris - Bercy-Seine Bus Station and Florence Villa Constanza Bus Station in around 21h 57m.

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