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How to get fromKey West to Biloxiby plane, shuttle, bus, car, or bus (Greyhound, Flixbus)

Find Transport to Biloxi

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There are 6 ways to get from Key West to Biloxi by plane, shuttle, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    4h 47m
    $142–549

  2. Fly to Mobile Regional Airport, bus

    cheapest
    1. Fly from Key West International Airport (EYW) to Mobile Regional Airport (MOB)plane plane EYW - MOB
    2. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    6h 55m
    $125–478

  3. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    24h 51m
    $342–455

  4. Drive  916.8 mi

    1. Drive from Key West to Biloxicar car 916.8 mi
    16h 32m
    $168–242

  5. Bus via Sandy Springs

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Biloxibus bus
    27h 30m
    $210–322

  6. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    29h 12m
    $155–258

Key West to Biloxi by bus and foot

Calendar7Weekly Services
Duration29h 12mAverage Duration
Ticket$155Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to Biloxi.ExpandLaunch map view
  • Distance: 619.8 mi
  • Duration: 4h 47m

What companies run services between Key West, FL, USA and Biloxi, MS, USA?

Delta, American Airlines, and Breeze Airways fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT) 5 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Biloxi via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, Garnett Station, Doraville Station, and Atlanta in around 27h 30m.

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