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How to get fromKey West to Biloxiby plane, bus (Greyhound, Flixbus), car or bus (Greyhound)

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There are 4 ways to get from Key West to Biloxi by plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    5h 17m
    $157–659

  2. Bus via Tallahassee

    cheapest
    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    25h 26m
    $136–303

  3. Drive 916.9 mi

    1. Drive from Key West to Biloxicar car 916.9 mi
    16h 31m
    $168–242

  4. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Dolphin Mall - Miami to Love's Travel Stop - Biloxibus bus
    26h 27m
    $184–363

Key West to Biloxi by bus and foot

Calendar13Weekly Services
Duration25h 26mAverage Duration
Ticket$136Cheapest Price
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Questions & Answers

What companies run services between Key West, FL, USA and Biloxi, MS, USA?

Delta, American Airlines, and Breeze Airways fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Biloxi Transit Center via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, and Mobile Bus Station in around 25h 26m.

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