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Frederick to Durham buses

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Trip Overview

The average bus between Frederick and Durham takes 10h 47m and the fastest bus takes 8h 45m. The bus service runs several times per day from Frederick to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 47m
Duration
331 mi
Distance
$69
Average price
3 times a day
Frequency

Frederick to Durham bus times

Buses run 3 times a day between Frederick and Durham. The earliest departure is at 5:05 AM in the morning, and the last departure from Frederick is at 11:40 PM which arrives into Durham at 8:25 AM. All services require a transfer, and take on average 10h 47m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USA8h 45m • 1 change

Departing Monday, November 16, 2026

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    Greyhound USAFlixbus USA9h 40m • 1 change
  •  → 

    Greyhound USAFlixbus USA11h 35m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA8h 45m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Greyhound USAGreyhound USA11h 5m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA15h 5m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA8h 45m • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    Greyhound USAGreyhound USA11h 5m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA15h 5m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA8h 45m • 1 change

Departing Thursday, November 19, 2026

  •  → 

    Greyhound USAGreyhound USA11h 5m • 1 change
  •  → 

    Greyhound USAFlixbus USA11h 35m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA8h 45m • 1 change

Departing Friday, November 20, 2026

  •  → 

    Greyhound USAFlixbus USA9h 40m • 1 change
  •  → 

    Greyhound USAFlixbus USA11h 35m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA8h 45m • 1 change

Departing Saturday, November 21, 2026

  •  → 

    Greyhound USAFlixbus USA9h 40m • 1 change
  •  → 

    Greyhound USAFlixbus USA11h 35m • 1 change

Frequently asked questions

Want to know about travelling from Frederick to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Frederick to Durham.ExpandLaunch map view
  • Distance: 330.6 mi
  • Duration: 10h 47m

What companies run services between Frederick, MD, USA and Durham, NC, USA?

You can take a bus from Frederick Bus Station to Durham via Washington Union Station in around 7h 55m.

Operators