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How to get fromFrederick to Durhamby bus (Greyhound, Flixbus), train (Amtrak), car, bus, plane, train or subway

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There are 8 ways to get from Frederick to Durham by bus (Greyhound, Flixbus), train (Amtrak), car, bus, plane, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Frederick Bus Station to Washington Union StationbusGreyhound US0164 / ...
    2. Take the bus from Washington Union Station to DurhambusFlixBus N2471 / ...
    7h 15m
    $52–170

  2. Train via Raleigh

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain
    2. Take the train from Washington Union Station to Raleigh Union Stationtrain
    3. Take the train from Raleigh Union Station to Durham Amtrak Stationtrain
    10h 3m
    $62–363

  3. Drive 296.5 mi

    1. Drive from Frederick to Durhamcar296.5 mi
    5h 5m
    $55–79

  4. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
    2. Fly from Baltimore-Washington International Airport (BWI) to Raleigh-Durham International Airport (RDU)planeBWI - RDU
    4h 47m
    $219–480

  5. Train, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrainMarc
    2. Take the bus from Springfield Bus Stop to DurhambusGreyhound US0670
    9h 59m
    $56–133

  6. Train

    1. Take the train from FREDERICK MARC eb to Washington Union StationtrainMarc
    2. Take the train from Washington Union Station to Durham Amtrak StationtrainCarolinian
    10h 30m
    $52–182

  7. Train, subway to Ronald Reagan Washington National Airport, fly, bus, line 700 bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
    2. Take the subway from Rockville, Red Line Center Platform to Gallery Place, Red Line Track 1 Platformsubway
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Raleigh-Durham International Airport (RDU)planeDCA - RDU
    4. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    5. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    5h 37m
    $96–623

  8. Bus to Washington Dulles International Airport, fly

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus
    2. Fly from Washington Dulles International Airport (IAD) to Raleigh-Durham International Airport (RDU)planeIAD - RDU
    5h 56m
    $164–529

Frederick to Durham by bus

Calendar21Weekly Buses
Duration7h 15mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Durham, NC, USA?

You can take a bus from Frederick Bus Station to Durham via Washington Union Station in around 7h 15m. Alternatively, you can take a train from FREDERICK MARC eb to Durham Amtrak Station via Washington Union Station and Raleigh Union Station in around 10h 3m.

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