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How to get fromFrederick to Durhamby bus (Greyhound, Flixbus), train (Amtrak), car, bus, plane, train, or subway

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There are 9 ways to get from Frederick to Durham by bus (Greyhound, Flixbus), train (Amtrak), car, bus, plane, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Frederick Bus Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Washington Union Station to Durhambus bus FlixBus N2471 / ...
    7h 15m
    $37–99

  2. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train Marc
    2. Take the train from Washington Union Station to Durham Amtrak Stationtrain train Carolinian
    9h 30m
    $97–222

  3. Drive 295.6 mi

    1. Drive from Frederick to Durhamcar car 295.6 mi
    5h 10m
    $54–78

  4. Bus to Baltimore-Washington International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Raleigh-Durham International Airport (RDU)plane plane BWI - RDU
    4h 43m
    $289–740

  5. Train, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train Marc
    2. Take the bus from Springfield Bus Stop to Durhambus bus Greyhound US0670
    9h 59m
    $51–113

  6. Train, subway to Ronald Reagan Washington National Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Rockville, Red Line Center Platform to Gallery Place, Red Line Track 1 Platformsubway subway
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Raleigh-Durham International Airport (RDU)plane plane DCA - RDU
    4. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    5. Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus bus
    5h 34m
    $71–523

  7. Bus to Washington Dulles International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Raleigh-Durham International Airport (RDU)plane plane IAD - RDU
    5h 51m
    $324–879

  8. Train to Ronald Reagan Washington National Airport, fly to Piedmont Triad International Airport, train

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Piedmont Triad International Airport (GSO)plane plane DCA - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    6h 27m
    $145–790

  9. Bus to Washington Dulles International Airport, fly to Piedmont Triad International Airport, train

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Piedmont Triad International Airport (GSO)plane plane IAD - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    6h 43m
    $93–456

Frederick to Durham by bus

Calendar21Weekly Buses
Duration7h 15mAverage Duration
Ticket$37Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Durham, NC, USA?

You can take a bus from Frederick Bus Station to Durham via Washington Union Station in around 7h 15m. Alternatively, you can take a train from FREDERICK MARC eb to Durham Amtrak Station via Washington Union Station in around 9h 30m.

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