The average bus between Denver and Durham takes 44h 59m and the fastest bus takes 41h 40m. The bus service runs several times per day from Denver to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Denver and Durham. The earliest departure is at 1:20 PM in the afternoon, and the last departure from Denver is at 7:25 PM which arrives into Durham at 9:10 PM. All services require a transfer at St Louis Bus Station and take an average of 44h 59m. The schedules shown below are for the next available departures.
Arrives +2 days


43h 40m • 2 changes
Arrives +2 days


2d 1h • 2 changes
Arrives +2 days


43h 40m • 2 changes
Arrives +2 days


2d 1h • 2 changes
Arrives +2 days


43h 40m • 2 changes
Arrives +2 days


2d 1h • 2 changes
Want to know about travelling from Denver to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Denver to Durham. However, there are services departing from Denver station and arriving at Durham station via St Louis Bus Station station. The journey, including transfers, takes approximately 44h 59m.
Denver to Durham bus services, operated by Greyhound USA, depart from Denver Union Station.
Denver to Durham bus services, operated by Greyhound USA, arrive at Durham station.
Book your Denver to Durham bus tickets online with Greyhound USA and Flixbus USA.
The distance between Denver and Durham is 2,318.9 km. The road distance is 2,914 km.
You can take a bus from Denver Union Station to Durham via St Louis Bus Station and Atlanta Bus Station in around 37h 40m.