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Des Moines to Durham buses

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Trip Overview

The bus between Des Moines and Durham takes 2d. The bus runs, on average, 5 times per week from Des Moines to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
1,142 mi
Distance
$245
Average price
5 times a week
Frequency

Des Moines to Durham bus times

Buses run 5 times a week between Des Moines and Durham. The service departs Des Moines at 7:50 AM in the morning, which arrives into Durham at 08:50:00. All services require a transfer at Indianapolis Union Station and take an average of 2d. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA2d • 3 changes

Departing Friday, November 13, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA2d • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA2d • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA2d • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA2d • 3 changes

Frequently asked questions

Want to know about travelling from Des Moines to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Durham.ExpandLaunch map view
  • Distance: 1,142 mi
  • Duration: 2d

What companies run services between Des Moines, IA, USA and Durham, NC, USA?

You can take a bus from Des Moines to Durham via Indianapolis Union Station, Columbus, and Winston Salem(Trans Center) in around 28h 40m.

Operators