The bus between Des Moines and St. Louis takes 8h 15m. There is at least one bus per day from Des Moines to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Des Moines and St. Louis. The earliest departure is at 4:20 PM in the afternoon, and the last departure from Des Moines is at 4:20 PM which arrives into St. Louis at 12:35 AM. All services run direct with no transfers required, and take on average 8h 15m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Des Moines station and arriving at St. Louis station. Services depart once daily, and operate Once daily. The journey takes approximately 8h 15m.
Des Moines to St. Louis bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Des Moines to St. Louis bus tickets online with Greyhound USA.
The distance between Des Moines and St. Louis is 439.8 km. The road distance is 668 km.
Greyhound USA operates a bus from Des Moines to St Louis Bus Station once daily. Tickets cost $65–130 and the journey takes 8h 15m.
