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Des Moines to Memphis buses

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Trip Overview

The average bus between Des Moines and Memphis takes 26h 59m and the fastest bus takes 26h 6m. The bus runs, on average, 4 times per week from Des Moines to Memphis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 59m
Duration
747 mi
Distance
$184
Average price
4 times a week
Frequency

Des Moines to Memphis bus times

Buses run 4 times a week between Des Moines and Memphis. The service departs Des Moines at 4:20 AM at night, which arrives into Memphis at 05:26:55. All services require a transfer at Kansas City and take an average of 26h 59m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USAMATA Transit26h 6m • 3 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USAMATA Transit26h 6m • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USAMATA Transit26h 6m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USAMATA Transit29h 36m • 3 changes

Frequently asked questions

Want to know about travelling from Des Moines to Memphis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Memphis.ExpandLaunch map view
  • Distance: 747.3 mi
  • Duration: 26h 59m

What companies run services between Des Moines, IA, USA and Memphis, TN, USA?

You can take a bus from Des Moines to 3RD STREET at EXCHANGE AVENUE via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Airways Transit Center in around 16h 17m.

Operators