There are 6 ways to get from Des Moines to Memphis by plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Memphis
best- Fly from Des Moines (DSM) to Memphis (MEM)plane DSM - MEM
5h 38m$229–1,222Bus
cheapest- Take the bus from Des Moines to Kansas Citybus Jefferson 803 / ...
- Take the bus from Kansas City to Memphis Bus Stationbus Jefferson 121
15h 52m$64–259Drive 596.3 mi
- Drive from Des Moines to Memphiscar 596.3 mi
10h 54m$109–158Fly Des Moines to Bill And Hillary Clinton National Airport, bus
- Fly from Des Moines (DSM) to Bill And Hillary Clinton National Airport (LIT)plane DSM - LIT
- Take the bus from Shell Gas Station - Little Rock, AR to Tornado Bus Co - West Memphisbus
8h 19m$214–861Drive to Fort Dodge Municipal Airport, fly to Memphis
- Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car
- Fly from Fort Dodge Municipal Airport (FOD) to Memphis (MEM)plane FOD - MEM
7h 44m$128–676Bus, train
- Take the bus from Des Moines to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
18h 43m$84–199
Des Moines to Memphis by bus
Questions & Answers
The cheapest way to get from Des Moines to Memphis is to drive which costs $100 - $160 and takes 10h 54m.
The fastest way to get from Des Moines to Memphis is to fly which takes 5h 38m and costs $220 - $1,300.
No, there is no direct bus from Des Moines to Memphis. However, there are services departing from Des Moines and arriving at 3RD STREET at EXCHANGE AVENUE via Kansas City and Airways Transit Center. The journey, including transfers, takes approximately 15h 52m.
The distance between Des Moines and Memphis is 513 miles. The road distance is 599.8 miles.
The best way to get from Des Moines to Memphis without a car is to bus which takes 15h 52m and costs $60 - $260.
It takes approximately 5h 38m to get from Des Moines to Memphis, including transfers.
Des Moines to Memphis bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Des Moines to Memphis is to fly which takes 5h 38m and costs $220 - $1,300. Alternatively, you can bus, which costs $60 - $260 and takes 15h 52m.
Des Moines to Memphis bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Des Moines to Memphis is 600 miles. It takes approximately 10h 54m to drive from Des Moines to Memphis.
What companies run services between Des Moines, IA, USA and Memphis, TN, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Memphis (MEM) every 2 hours. Alternatively, you can take a bus from Des Moines to 3RD STREET at EXCHANGE AVENUE via Kansas City and Airways Transit Center in around 15h 52m.
- Website
- aa.com
Flights from Des Moines to Memphis via Chicago O'Hare
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $210–1,200
Flights from Des Moines to Memphis via Dallas/Ft.Worth
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $250–1,300
Flights from Des Moines to Bill And Hillary Clinton National Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $150–800
Flights from Des Moines to Bill And Hillary Clinton National Airport via Chicago O'Hare
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $140–750
- Website
- delta.com
Flights from Des Moines to Memphis via Atlanta
- Ave. Duration
- 5h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $260–1,300
Flights from Des Moines to Memphis via Minneapolis
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Des Moines to Memphis via Detroit
- Ave. Duration
- 5h 56m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $270–1,400
Flights from Des Moines to Bill And Hillary Clinton National Airport via Atlanta
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $170–900
- Website
- united.com
Flights from Des Moines to Memphis via Chicago O'Hare
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $210–1,200
Flights from Des Moines to Bill And Hillary Clinton National Airport via Houston
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $170–900
Flights from Des Moines to Bill And Hillary Clinton National Airport via Chicago O'Hare
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $140–750
Flights from Fort Dodge Municipal Airport to Memphis via Chicago O'Hare
- Ave. Duration
- 5h 50m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
- Website
- southwest.com
Flights from Des Moines to Memphis via Chicago Midway
- Ave. Duration
- 3h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $210–1,200
Flights from Des Moines to Bill And Hillary Clinton National Airport via St. Louis
- Ave. Duration
- 4h 30m
- When
- Monday and Sunday
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Bus from Kansas City to Memphis Bus Station
- Ave. Duration
- 10h
- Frequency
- 4 times a week
- Estimated price
- $45–170
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Shell Gas Station - Little Rock, AR to Tornado Bus Co - West Memphis
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $45–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–140
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $40–60
- Schedules at
- flixbus.com
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