The average bus between Des Moines and Cape Cod takes 2d 1h and the fastest bus takes 2d. There is at least one bus per day from Des Moines to Cape Cod. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Des Moines and Cape Cod. The earliest departure is at 9:20 AM in the morning, and the last departure from Des Moines is at 9:45 AM which arrives into Cape Cod at 2:48 PM. All services require a transfer at Chicago Bus Station and take an average of 2d 1h. The schedules shown below are for the next available departures.
Arrives +2 days




2d 1h • 4 changes
Arrives +2 days




2d 5h • 4 changes
Arrives +2 days




2d 1h • 4 changes
Arrives +2 days




2d 5h • 4 changes
Want to know about travelling from Des Moines to Cape Cod? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Cape Cod. However, there are services departing from Des Moines station and arriving at Cape Cod station via Chicago Bus Station station. The journey, including transfers, takes approximately 2d 1h.
Des Moines to Cape Cod bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Cape Cod bus services, operated by Greyhound USA, arrive at Hyannis Transportation Center station.
The distance between Des Moines and Cape Cod is 1,939.3 km. The road distance is 2,599 km.
You can take a bus from Des Moines to Town Hall Lawton Bus Shelter via Chicago Bus Station, New York Midtown, Boston, Boston South Station, and Hyannis Transportation Center in around 37h 16m.