There are 8 ways to get from Des Moines to Cape Cod by plane, bus, train, bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Boston Logan Airport, bus
best- Fly from Des Moines (DSM) to Boston Logan Airport (BOS)DSM - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Center
6h 53m$189–764Bus, train
- Take the bus from Des Moines to Chicago
- Take the train from Chicago Union Station to Boston
- Take the bus from Boston South Station to Hyannis Transportation Center
32h 50m$211–836Bus
- Take the bus from Des Moines to Chicago
- Take the bus from Chicago Bus Station to New York Midtown
- Take the bus from New York Midtown to Boston
- Take the bus from Boston South Station to Hyannis Transportation Center
36h 9m$211–481Drive 1,345.5 mi
- Drive from Des Moines to Cape Cod1,345.5 mi
22h 54m$246–355Fly to Barnstable Municipal Airport
- Fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA)DSM - HYA
7h 2m$204–977Bus, train via Des Moines
- Take the bus from Des Moines to Chicago
- Take the train from Chicago Union Station to Boston
- Take the bus from Boston South Buses to Hyannis Transportation Center
33h 53m$216–842Bus, train via Des Moines #2
- Take the bus from Des Moines to Chicago Bus Station
- Take the train from Chicago Union Station to Boston
- Take the bus from Boston South Buses to Hyannis Transportation Center
34h 33m$202–761Bus, train via Galesburg
- Take the bus from Des Moines to Burlington
- Take the bus from Burlington to Galesburg
- Take the train from Galesburg Amtrak Station to Chicago Union Station
- Take the train from Chicago Union Station to Boston
- Take the bus from Boston South Station to Hyannis Transportation Center
35h 26m$229–880
Des Moines to Cape Cod by bus, foot, and train
Questions & Answers
The cheapest way to get from Des Moines to Cape Cod is to drive which costs $240 - $360 and takes 22h 54m.
The fastest way to get from Des Moines to Cape Cod is to fly and bus which takes 6h 53m and costs $180 - $800.
No, there is no direct bus from Des Moines to Cape Cod. However, there are services departing from Des Moines and arriving at Town Hall Lawton Bus Shelter via Chicago Bus Station, New York Midtown, Boston South Station and Hyannis Transportation Center. The journey, including transfers, takes approximately 36h 9m.
The distance between Des Moines and Cape Cod is 1259 miles. The road distance is 1353.4 miles.
The best way to get from Des Moines to Cape Cod without a car is to bus and train which takes 32h 50m and costs $210 - $850.
It takes approximately 6h 53m to get from Des Moines to Cape Cod, including transfers.
Des Moines to Cape Cod bus services, operated by Burlington Trailways, depart from Des Moines station.
The best way to get from Des Moines to Cape Cod is to bus which takes 36h 9m and costs $210 - $490. Alternatively, you can fly, which costs $200 - $1,000 and takes 7h 2m.
Des Moines to Cape Cod bus services, operated by Burlington Trailways, arrive at Chicago station.
Yes, the driving distance between Des Moines to Cape Cod is 1353 miles. It takes approximately 22h 54m to drive from Des Moines to Cape Cod.
What companies run services between Des Moines, IA, USA and Cape Cod, MA, USA?
You can take a bus from Des Moines to Town Hall Lawton Bus Shelter via Chicago Bus Station, New York Midtown, Boston, Boston South Station, and Hyannis Transportation Center in around 36h 9m. Alternatively, American Airlines, Allegiant Air, and two other airlines fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA) twice daily.
- Website
- aa.com
Flights from Des Moines to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Boston Logan Airport via Philadelphia
- Ave. Duration
- 5h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Des Moines to Barnstable Municipal Airport via New York La Guardia
- Ave. Duration
- 5h 17m
- When
- Monday to Friday
- Estimated price
- $190–950
Flights from Des Moines to Barnstable Municipal Airport via Reagan Washington
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Des Moines to Barnstable Municipal Airport via Chicago O'Hare
- Ave. Duration
- 6h 37m
- When
- Saturday
- Estimated price
- $180–950
- Website
- united.com
Flights from Des Moines to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Des Moines to Boston Logan Airport via Detroit
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $140–700
Flights from Des Moines to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 5h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
- Website
- southwest.com
Flights from Des Moines to Boston Logan Airport via St. Louis
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Des Moines to Boston Logan Airport via Chicago Midway
- Ave. Duration
- 6h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $140–700
- Website
- allegiantair.com
Flights from Des Moines to Boston Logan Airport
- Ave. Duration
- 2h 55m
- When
- Monday and Friday
- Estimated price
- $140–700
- Website
- capeair.com
Flights from Des Moines to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 5h
- When
- Monday
- Estimated price
- $190–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Boston
- Ave. Duration
- 22h 2m
- Frequency
- Once daily
- Estimated price
- $130–650
- Website
- https://www.amtrak.com/home.html
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $20–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Logan International Airport to Hyannis Transportation Center
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com
- One Way - Adult
- $28–40
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- https://www.p-b.com
- One Way - Adult
- $27–35
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Chicago
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $65–143
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–100
- Flexible Fares
- $90–140
- Saver Fare
- $104
- Flex Fare
- $143
Bus from Des Moines to Burlington
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Burlington to Galesburg
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Boston South Station to Hyannis Transportation Center
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $10–40
- Website
- https://peterpanbus.com
- Adult
- $10–40
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to New York Midtown
- Ave. Duration
- 20h 10m
- Frequency
- Once daily
- Estimated price
- $100–230
- Schedules at
- flixbus.com
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Every 3 hours
- Estimated price
- $30–65
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
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