There are 6 ways to get from Des Moines to Cape Cod by plane, bus, train, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Barnstable Municipal Airport
best- Fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA)plane DSM - HYA
5h 32m$428–1,361Fly to Boston Logan Airport, bus
cheapest- Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane DSM - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
7h 10m$199–814Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Bostontrain
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus
34h 6m$368–796Bus
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis to New York Midtownbus
- Take the bus from New York Midtown to Bostonbus
- Take the bus from Boston South Station to Hyannis Transportation Centerbus
36h 10m$225–417Drive 1,345.5 mi
- Drive from Des Moines to Cape Codcar 1,345.5 mi
23h 7m$246–355Bus, train via Bloomington
- Take the bus from Des Moines to Bloomington-Normalbus
- Take the train from Bloomington-Normal to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bostontrain
- Take the bus from Boston South Station to Barnstablebus
35h 1m$419–914
Des Moines to Cape Cod by bus, foot, and train
Questions & Answers
The cheapest way to get from Des Moines to Cape Cod is to bus which costs $220 - $420 and takes 36h 10m.
The fastest way to get from Des Moines to Cape Cod is to fly which takes 5h 32m and costs $420 - $1,400.
No, there is no direct bus from Des Moines to Cape Cod. However, there are services departing from Des Moines and arriving at Town Hall Lawton Bus Shelter via Indianapolis, New York Midtown, Boston South Station and Hyannis Transportation Center. The journey, including transfers, takes approximately 36h 10m.
The distance between Des Moines and Cape Cod is 1224 miles. The road distance is 1353.4 miles.
The best way to get from Des Moines to Cape Cod without a car is to bus and train which takes 34h 6m and costs $360 - $800.
It takes approximately 5h 32m to get from Des Moines to Cape Cod, including transfers.
Des Moines to Cape Cod bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Cape Cod is to fly which takes 5h 32m and costs $420 - $1,400. Alternatively, you can bus, which costs $220 - $420 and takes 36h 10m.
Des Moines to Cape Cod bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Yes, the driving distance between Des Moines to Cape Cod is 1353 miles. It takes approximately 23h 7m to drive from Des Moines to Cape Cod.
What companies run services between Des Moines, IA, USA and Cape Cod, MA, USA?
American Airlines and United Airlines fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA) twice daily. Alternatively, you can take a bus from Des Moines to Town Hall Lawton Bus Shelter via Indianapolis, Illinois St (Greyhound Bus Station), Indianapolis, New York Midtown, Boston, Boston South Station, and Hyannis Transportation Center in around 36h 10m.
- Website
- aa.com
Flights from Des Moines to Barnstable Municipal Airport via Philadelphia
- Ave. Duration
- 5h 9m
- When
- Thursday
- Estimated price
- $220–1,100
Flights from Des Moines to Barnstable Municipal Airport via Chicago O'Hare
- Ave. Duration
- 7h 8m
- When
- Saturday
- Estimated price
- $210–1,100
Flights from Des Moines to Barnstable Municipal Airport via Reagan Washington
- Ave. Duration
- 10h 37m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Des Moines to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Boston Logan Airport via Philadelphia
- Ave. Duration
- 5h 24m
- When
- Thursday
- Estimated price
- $160–800
- Website
- united.com
Flights from Des Moines to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $150–750
- Website
- delta.com
Flights from Des Moines to Boston Logan Airport via Detroit
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 4h 56m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
- Website
- southwest.com
Flights from Des Moines to Boston Logan Airport via Chicago Midway
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
- Website
- allegiantair.com
Flights from Des Moines to Boston Logan Airport
- Ave. Duration
- 2h 49m
- When
- Thursday and Sunday
- Estimated price
- $150–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Boston
- Ave. Duration
- 22h 2m
- Frequency
- Once daily
- Estimated price
- $280–650
- Website
- https://www.amtrak.com/home.html
Train from Bloomington-Normal to Chicago Union Station
- Ave. Duration
- 2h 19m
- Frequency
- 5 times a day
- Estimated price
- $35–80
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Des Moines to Bloomington-Normal
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $50–95
- Website
- https://www.greyhound.com/
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- https://www.p-b.com/
- One Way - Adult
- $27–35
Bus from Logan International Airport to Hyannis Transportation Center
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com/
- One Way - Adult
- $28–40
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Indianapolis to New York Midtown
- Ave. Duration
- 16h 10m
- Frequency
- Twice daily
- Estimated price
- $100–180
- Schedules at
- flixbus.com
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $28–50
- Schedules at
- flixbus.com
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Boston South Station to Hyannis Transportation Center
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $14–35
- Website
- https://peterpanbus.com
Bus from Boston South Station to Barnstable
- Ave. Duration
- 1h 15m
- Frequency
- Every 3 hours
- Estimated price
- $14–35
- Website
- https://peterpanbus.com
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