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How to get fromDes Moines to Cape Codby plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 6 ways to get from Des Moines to Cape Cod by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barnstable Municipal Airport

    best
    1. Fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA)plane plane DSM - HYA
    5h 32m
    $458–1,461
  2. Fly to Boston Logan Airport, bus

    cheapest
    1. Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane plane DSM - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    7h 10m
    $219–964
  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    35h 6m
    $371–800
  4. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    4. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
    38h 21m
    $226–425
  5. Drive 1,345.5 mi

    1. Drive from Des Moines to Cape Codcar car 1,345.5 mi
    23h 7m
    $246–355
  6. Bus, train via Saint Paul

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bostontrain train
    4. Take the bus from Boston South Station to Barnstablebus bus
    38h 41m
    $468–1,094

Des Moines to Cape Cod by bus, foot, and train

Calendar7Weekly Services
Duration35h 6mAverage Duration
Ticket$371Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Cape Cod, MA, USA?

American Airlines and United Airlines fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA) twice daily. Alternatively, you can take a bus from Des Moines to Town Hall Lawton Bus Shelter via Chicago Bus Station, New York Midtown, Boston, Boston South Station, and Hyannis Transportation Center in around 38h 21m.

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