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How to get fromDes Moines to Cape Codby plane, bus, train, bus (Greyhound, Flixbus), car or taxi

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There are 6 ways to get from Des Moines to Cape Cod by plane, bus, train, bus (Greyhound, Flixbus), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Boston Logan Airport, bus

    best
    1. Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane plane DSM - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    7h 10m
    $239–1,014
  2. Bus, train

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    34h 6m
    $159–494
  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    4. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
    37h 25m
    $182–449
  4. Drive 1,345.5 mi

    1. Drive from Des Moines to Cape Codcar car 1,345.5 mi
    23h 7m
    $246–355
  5. Fly to Barnstable Municipal Airport

    1. Fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA)plane plane DSM - HYA
    8h 7m
    $204–927
  6. Fly to Provincetown Municipal Airport, taxi

    1. Fly from Des Moines (DSM) to Provincetown Municipal Airport (PVC)plane plane DSM - PVC
    2. Take the taxi from Provincetown Municipal Airport (PVC) to Cape Codtaxi taxi
    17h 46m
    $768–2,291

Des Moines to Cape Cod by bus, foot, and train

Calendar7Weekly Services
Duration34h 6mAverage Duration
Ticket$159Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Cape Cod, MA, USA?

You can take a bus from Des Moines to Town Hall Lawton Bus Shelter via Chicago Bus Station, New York Midtown, Boston, Boston South Station, and Hyannis Transportation Center in around 37h 25m. Alternatively, American Airlines and United Airlines fly from Des Moines (DSM) to Barnstable Municipal Airport (HYA) twice daily.

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