There are 4 ways to get from Tupelo to Picayune by car, plane, taxi, bus (Greyhound, Flixbus), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, fly, taxi
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Gulfport-Biloxi Regional Airport (GPT)plane GTR - GPT
- Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi
5h 45m$191–576Drive 292.2 mi
cheapest- Drive from Tupelo to Picayunecar 292.2 mi
5h 14m$54–77Bus
- Take the bus from Tupelo to Memphis Bus Stationbus Greyhound US0610
- Take the bus from Memphis Bus Station to Slidellbus Greyhound US1173
11h 27m$134–252Bus, train
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Jacksonbus
- Take the train from Jackson to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain
14h 36m$110–210
Golden Triangle Regional Airport (GTR) to Gulfport-Biloxi Regional Airport (GPT) flights
Questions & Answers
The cheapest way to get from Tupelo to Picayune is to drive which costs $50 - $80 and takes 5h 14m.
The fastest way to get from Tupelo to Picayune is to drive which takes 5h 14m and costs $50 - $80.
The distance between Tupelo and Picayune is 321 miles. The road distance is 293.9 miles.
The best way to get from Tupelo to Picayune without a car is to bus which takes 11h 27m and costs $130 - $260.
It takes approximately 5h 45m to get from Tupelo to Picayune, including transfers.
Yes, the driving distance between Tupelo to Picayune is 294 miles. It takes approximately 5h 14m to drive from Tupelo to Picayune.
There are eight+ hotels available in Picayune.
What companies run services between Tupelo, MS, USA and Picayune, MS, USA?
You can take a vehicle from Tupelo to Picayune via Tupelo, Memphis Bus Station, and Slidell in around 11h 27m.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $70–420
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $100–500
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jackson to New Orleans Union Passenger Terminal
- Ave. Duration
- 4h 27m
- Frequency
- Once daily
- Estimated price
- $28–70
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Picayune Amtrak Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $14–18
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Slidell
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Jackson
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $29–50
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Memphis Bus Station to Slidell
- Ave. Duration
- 6h 50m
- Frequency
- 5 times a week
- Estimated price
- $40–95
- Schedules at
- flixbus.com
- Adult
- $40–95
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