There are 5 ways to get from Tupelo to Mobile by car, plane, bus (Greyhound), bus, train, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly to Mobile Regional Airport
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Mobile Regional Airport (MOB)plane GTR - MOB
6h 49m$101–425Drive 274.4 mi
cheapest- Drive from Tupelo to Mobilecar 274.4 mi
5h 25m$47–68Bus (Greyhound)
- Take the bus from Tupelo to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Bus Station to Mobile Bus Stationbus Greyhound US0602 / ...
13h 47m$121–189Bus, train
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Jacksonbus
- Take the train from Jackson to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
15h 30m$194–382Bus to Memphis, fly to Pensacola International Airport, taxi
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Pensacola International Airport (PNS)plane MEM - PNS
- Take the taxi from Pensacola-Airport-PNS to Mobiletaxi
6h 25m$240–623
Golden Triangle Regional Airport (GTR) to Mobile Regional Airport (MOB) flights
Comparing Your Travel Options
The cheapest way to get from Tupelo to Mobile is to drive which costs $45 - $70 and takes 5h 25m.
The fastest way to get from Tupelo to Mobile is to drive which takes 5h 25m and costs $45 - $70.
No, there is no direct bus from Tupelo to Mobile. However, there are services departing from Tupelo and arriving at Water NB at Dauphin St via Atlanta Bus Station and Govt EB at Greyhound Bus Station. The journey, including transfers, takes approximately 13h 47m.
The distance between Tupelo and Mobile is 269 miles. The road distance is 276 miles.
The best way to get from Tupelo to Mobile without a car is to bus which takes 13h 47m and costs $120 - $190.
It takes approximately 6h 49m to get from Tupelo to Mobile, including transfers.
Tupelo to Mobile bus services, operated by Greyhound USA, depart from Tupelo station.
Tupelo to Mobile bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Tupelo to Mobile is 276 miles. It takes approximately 5h 25m to drive from Tupelo to Mobile.
Book your Tupelo to Mobile bus tickets online with Omio.
What companies run services between Tupelo, MS, USA and Mobile, AL, USA?
You can take a vehicle from Tupelo to Water NB at Dauphin St via Tupelo, Atlanta Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 13h 47m.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Mobile Regional Airport via Atlanta
- Ave. Duration
- 5h 50m
- When
- Monday, Thursday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- $60–370
Flights from Memphis to Pensacola International Airport via Atlanta
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $70–410
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $90–450
- Website
- flybreeze.com
Flights from Memphis to Pensacola International Airport
- Ave. Duration
- 1h 23m
- When
- Thursday and Sunday
- Estimated price
- $150–900
- Website
- southwest.com
Flights from Memphis to Pensacola International Airport via Nashville
- Ave. Duration
- 3h 25m
- When
- Saturday
- Estimated price
- $70–410
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jackson to New Orleans Union Passenger Terminal
- Ave. Duration
- 3h 58m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- 4 times a day
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- Every 3 hours
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–28
- Website
- Greyhound
Bus from Memphis Bus Station to Jackson
- Ave. Duration
- 3h 55m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–28
- Website
- Greyhound
- Ave. Duration
- 58 min
- Estimated price
- $140–170
Able Shuttle and Taxi
- Phone
- +1 850-607-0209
Choice Taxi
- Phone
- +1 850-529-1806
- Website
- mychoicetaxi.com
Want to know more about travelling around United States
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Booking & Getting There
There are 211+ hotels available in Mobile.





