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How to get fromTupelo to Indianapolisby car, plane, bus (Greyhound, Flixbus), bus or bus (Greyhound)

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There are 7 ways to get from Tupelo to Indianapolis by car, plane, bus (Greyhound, Flixbus), bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Indianapolis (IND)plane plane GTR - IND
    7h 36m
    $88–458

  2. Drive 461.6 mi

    cheapest
    1. Drive from Tupelo to Indianapoliscar car 461.6 mi
    9h 47m
    $85–122

  3. Bus

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Indianapolisbus bus
    13h 19m
    $91–167

  4. Fly from Tupelo Regional Airport

    1. Fly from Tupelo Regional Airport (TUP) to Indianapolis (IND)plane plane TUP - IND
    6h 59m
    $103–621

  5. Bus to Memphis, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Indianapolis (IND)plane plane MEM - IND
    9h
    $114–595

  6. Bus via St. Louis

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    13h 34m
    $91–207

  7. Bus #2

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus Greyhound US0610
    2. Take the bus from Tornado Bus Co - West Memphis to Indianapolisbus bus Memphis
    14h 51m
    $136–276

Golden Triangle Regional Airport (GTR) to Indianapolis (IND) flights

Calendar20Weekly Planes
Duration6h 4mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

What companies run services between Tupelo, MS, USA and Indianapolis, IN, USA?

You can take a vehicle from Tupelo to Indianapolis via Tupelo, Memphis Bus Station, and Nashville Bus Station in around 13h 19m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and American Airlines fly from Tupelo Regional Airport (TUP) to Indianapolis (IND) twice daily.

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