There are 7 ways to get from Tupelo to Indianapolis by bus (Greyhound, Flixbus), car, plane, bus (Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via St. Louis
best- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
13h 4m$101–198Drive 464.4 mi
cheapest- Drive from Tupelo to Indianapoliscar 464.4 mi
9h 33m$85–123Drive to Golden Triangle Regional Airport, fly
- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Indianapolis (IND)plane GTR - IND
7h 51m$113–568Bus
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Indianapolisbus
14h 39m$101–183Bus #2
- Take the bus from Tupelo to Memphis Bus Stationbus Greyhound US0610
- Take the bus from Tornado Bus Co - West Memphis to Indianapolisbus Memphis
14h 50m$139–281Fly from Tupelo Regional Airport
- Fly from Tupelo Regional Airport (TUP) to Indianapolis (IND)plane TUP - IND
4h 54m$92–489Bus to Memphis, fly
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Indianapolis (IND)plane MEM - IND
8h 18m$129–696
Golden Triangle Regional Airport (GTR) to Indianapolis (IND) flights
Questions & Answers
The cheapest way to get from Tupelo to Indianapolis is to drive which costs $85 - $130 and takes 9h 33m.
The fastest way to get from Tupelo to Indianapolis is to fly which takes 4h 54m and costs $90 - $490.
No, there is no direct bus from Tupelo to Indianapolis station. However, there are services departing from Tupelo and arriving at Indianapolis Union Station via Memphis Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 13h 4m.
The distance between Tupelo and Indianapolis is 640 miles. The road distance is 467.1 miles.
The best way to get from Tupelo to Indianapolis without a car is to bus via St. Louis which takes 13h 4m and costs $100 - $200.
It takes approximately 13h 4m to get from Tupelo to Indianapolis, including transfers.
Tupelo to Indianapolis bus services, operated by Greyhound USA, depart from Tupelo station.
The best way to get from Tupelo to Indianapolis is to bus via St. Louis which takes 13h 4m and costs $100 - $200. Alternatively, you can fly, which costs $90 - $490 and takes 4h 54m.
Tupelo to Indianapolis bus services, operated by Greyhound USA, arrive at Memphis Bus Station.
Indianapolis is 1h ahead of Tupelo. It is currently 12:20 PM in Tupelo and 1:20 PM in Indianapolis.
What companies run services between Tupelo, MS, USA and Indianapolis, IN, USA?
You can take a vehicle from Tupelo to Indianapolis Union Station via Tupelo, Memphis Bus Station, and St Louis Bus Station in around 13h 4m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Indianapolis (IND) once daily.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Indianapolis via Atlanta
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $100–550
Flights from Tupelo Regional Airport to Indianapolis via Nashville, Atlanta
- Ave. Duration
- 8h 7m
- When
- Sunday
- Estimated price
- $110–600
Flights from Memphis to Indianapolis via Atlanta
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $140–750
Flights from Memphis to Indianapolis via Detroit
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $150–750
- Website
- southwest.com
Flights from Tupelo Regional Airport to Indianapolis via Nashville
- Ave. Duration
- 4h
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $75–470
Flights from Tupelo Regional Airport to Indianapolis via Nashville, Atlanta
- Ave. Duration
- 6h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–600
Flights from Tupelo Regional Airport to Indianapolis via Nashville, Chicago Midway
- Ave. Duration
- 6h 15m
- When
- Sunday
- Estimated price
- $100–550
Flights from Memphis to Indianapolis via Nashville
- Ave. Duration
- 3h 51m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $100–650
Flights from Memphis to Indianapolis via Dallas
- Ave. Duration
- 5h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $190–900
Flights from Memphis to Indianapolis via Chicago Midway
- Ave. Duration
- 6h 5m
- When
- Monday to Wednesday
- Estimated price
- $120–700
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $150–700
Flights from Tupelo Regional Airport to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 6h 4m
- When
- Thursday and Sunday
- Estimated price
- $150–700
Flights from Memphis to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $120–700
Flights from Memphis to Indianapolis via Charlotte
- Ave. Duration
- 4h 50m
- When
- Thursday to Friday
- Estimated price
- $160–800
- Website
- united.com
Flights from Memphis to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $120–700
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–29
- Website
- Greyhound
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–29
- Website
- Greyhound
Bus from Memphis Bus Station to Nashville Bus Station
- Ave. Duration
- 3h 50m
- Frequency
- 4 times a day
- Estimated price
- $30–60
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–29
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–29
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to Nashville Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 5 times a week
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from Nashville Bus Station to Indianapolis
- Ave. Duration
- 6h 55m
- Frequency
- Twice daily
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- Tornado Bus Company
Bus from Tornado Bus Co - West Memphis to Indianapolis
- Ave. Duration
- 9h 31m
- Frequency
- 3 times a week
- Estimated price
- $90–210
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $90–210
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More Questions & Answers
Yes, the driving distance between Tupelo to Indianapolis is 467 miles. It takes approximately 9h 33m to drive from Tupelo to Indianapolis.
Book your Tupelo to Indianapolis bus tickets online with Omio.
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