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How to get fromTupelo to Destinby bus, plane, taxi or car

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There are 9 ways to get from Tupelo to Destin by bus, plane, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Memphis, fly to Destin–Fort Walton Beach Airport

    best
    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Destin–Fort Walton Beach Airport (VPS)plane plane MEM - VPS
    5h 52m
    $134–515

  2. Drive 355 mi

    cheapest
    1. Drive from Tupelo to Destincar car 355 mi
    7h 58m
    $65–94

  3. Bus, taxi

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    15h 13m
    $254–367

  4. Fly Tupelo Regional Airport to Destin–Fort Walton Beach Airport

    1. Fly from Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS)plane plane TUP - VPS
    5h 46m
    $145–622

  5. Fly Tupelo Regional Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Tupelo Regional Airport (TUP) to Northwest Florida Beaches International Airport (ECP)plane plane TUP - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 48m
    $225–717

  6. Drive to Northwest Alabama Regional Airport, fly to Pensacola International Airport, taxi

    1. Drive from Tupelo to Northwest Alabama Regional Airport (MSL)car car
    2. Fly from Northwest Alabama Regional Airport (MSL) to Pensacola International Airport (PNS)plane plane MSL - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    4h 35m
    $220–492

  7. Fly Tupelo Regional Airport to Pensacola International Airport, taxi

    1. Fly from Tupelo Regional Airport (TUP) to Pensacola International Airport (PNS)plane plane TUP - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 22m
    $230–777

  8. Bus, taxi via Opelika

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Opelika 4th Street Stationbus bus
    3. Take the bus from Opelika 4th Street Station to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    16h 31m
    $265–399

  9. Bus, taxi #2

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Baton Rouge Bus Stationbus bus
    3. Take the bus from Baton Rouge Albertson's to McDonald's - Crestviewbus bus
    4. Take the taxi from McDonald's - Crestview to Destintaxi taxi
    22h 4m
    $255–504

Memphis (MEM) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar37Weekly Planes
Duration3h 14mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

What companies run services between Tupelo, MS, USA and Destin, FL, USA?

Corporate Flight Management Inc, American Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS) twice daily.

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