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How to get fromTupelo to Destinby plane, bus, taxi, car, or train

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There are 9 ways to get from Tupelo to Destin by plane, bus, taxi, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Tupelo Regional Airport to Destin–Fort Walton Beach Airport

    best
    1. Fly from Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS)plane plane TUP - VPS
    5h 58m
    $120–422

  2. Drive 355 mi

    cheapest
    1. Drive from Tupelo to Destincar car 355 mi
    7h 58m
    $65–94

  3. Bus, taxi

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    15h 21m
    $249–352

  4. Bus to Memphis, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Destin–Fort Walton Beach Airport (VPS)plane plane MEM - VPS
    7h 52m
    $156–578

  5. Fly Tupelo Regional Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Tupelo Regional Airport (TUP) to Northwest Florida Beaches International Airport (ECP)plane plane TUP - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    6h 7m
    $200–527

  6. Fly Tupelo Regional Airport to Pensacola International Airport, taxi

    1. Fly from Tupelo Regional Airport (TUP) to Pensacola International Airport (PNS)plane plane TUP - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 25m
    $200–537

  7. Drive to Northwest Alabama Regional Airport, fly to Pensacola International Airport, taxi

    1. Drive from Tupelo to Northwest Alabama Regional Airport (MSL)car car
    2. Fly from Northwest Alabama Regional Airport (MSL) to Pensacola International Airport (PNS)plane plane MSL - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    4h 35m
    $235–492

  8. Bus to Hartsfield-Jackson Atlanta International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Destin–Fort Walton Beach Airport (VPS)plane plane ATL - VPS
    8h 41m
    $144–492

  9. Bus, train, taxi

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    5. Take the bus from Mobile to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    19h 11m
    $265–477

Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar13Weekly Planes
Duration6h 7mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from Tupelo to Destin.ExpandLaunch map view
  • Distance: 311.1 mi
  • Duration: 5h 58m

What companies run services between Tupelo, MS, USA and Destin, FL, USA?

Corporate Flight Management Inc, American Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS) twice daily.

Airlines
Train operators
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