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How to get fromTupelo to Destinby car, plane, bus, taxi, or train

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There are 5 ways to get from Tupelo to Destin by car, plane, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Destin–Fort Walton Beach Airport (VPS)plane plane GTR - VPS
    5h 29m
    $111–431

  2. Drive  355 mi

    cheapest
    1. Drive from Tupelo to Destincar car 355 mi
    7h 57m
    $65–94

  3. Bus, taxi

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    15h 23m
    $254–342

  4. Fly from Tupelo Regional Airport

    1. Fly from Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS)plane plane TUP - VPS
    4h 10m
    $120–442

  5. Bus, train, taxi

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain train
    5. Take the bus from Pascagoula to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    18h 59m
    $264–465

Golden Triangle Regional Airport (GTR) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar32Weekly Planes
Duration5h 42mAverage Duration
Ticket$60Cheapest Price
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Comparing Your Travel Options

Map of how to get from Tupelo to Destin.ExpandLaunch map view
  • Distance: 314.7 mi
  • Duration: 5h 29m

What companies run services between Tupelo, MS, USA and Destin, FL, USA?

Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS) twice daily.

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