There are 4 ways to get from Tupelo to Lexington by car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly to Blue Grass Airport
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)
- Fly from Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX)GTR - LEX
7h$73–368Bus (Greyhound)
- Take the bus from Tupelo to Atlanta Bus StationGreyhound US0610
- Take the bus from Atlanta Bus Station to Lexington Bus StopGreyhound US0110
14h 26m$132–274Drive 412.1 mi
- Drive from Tupelo to Lexington412.1 mi
7h 58m$76–109Fly Tupelo Regional Airport to Louisville International Airport, drive
- Fly from Tupelo Regional Airport (TUP) to Louisville International Airport (SDF)TUP - SDF
- Drive from Louisville-Airport-SDF to Lexington
7h 4m$130–510
Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX) flights
Questions & Answers
The cheapest way to get from Tupelo to Lexington is to drive which costs $75 - $110 and takes 7h 58m.
The fastest way to get from Tupelo to Lexington is to drive and fly which takes 7h and costs $70 - $370.
The distance between Tupelo and Lexington is 467 miles. The road distance is 414.5 miles.
The best way to get from Tupelo to Lexington without a car is to bus which takes 14h 26m and costs $130 - $280.
It takes approximately 7h to get from Tupelo to Lexington, including transfers.
Lexington is 1h ahead of Tupelo. It is currently 5:12 PM in Tupelo and 6:12 PM in Lexington.
Yes, the driving distance between Tupelo to Lexington is 414 miles. It takes approximately 7h 58m to drive from Tupelo to Lexington.
There are 143+ hotels available in Lexington.
What companies run services between Tupelo, MS, USA and Lexington, KY, USA?
You can take a vehicle from Tupelo to Lexington via Tupelo, Atlanta Bus Station, and Lexington Bus Stop in around 14h 26m.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $60–350
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville, Atlanta
- Ave. Duration
- 7h 24m
- When
- Friday to Sunday
- Estimated price
- $100–550
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 19m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–490
Flights from Tupelo Regional Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 17m
- When
- Saturday and Sunday
- Estimated price
- $140–700
- Website
- southwest.com
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville
- Ave. Duration
- 7h 10m
- When
- Monday
- Estimated price
- $100–470
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville, Chicago Midway
- Ave. Duration
- 8h 5m
- When
- Monday
- Estimated price
- $110–600
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $45–120
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Lexington Bus Stop
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
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