There are 7 ways to get from Tupelo to Lexington by car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly to Blue Grass Airport
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX)plane GTR - LEX
6h 56m$68–368Bus, drive via Brentwood
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Nashville Bus Stationbus
- Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
15h 20m$139–330Drive 412.1 mi
- Drive from Tupelo to Lexingtoncar 412.1 mi
8h$76–109Fly Tupelo Regional Airport to Louisville International Airport, drive
- Fly from Tupelo Regional Airport (TUP) to Louisville International Airport (SDF)plane TUP - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
8h 10m$140–520Fly Tupelo Regional Airport to Covington, drive
- Fly from Tupelo Regional Airport (TUP) to Covington (CVG)plane TUP - CVG
- Drive from Covington (CVG) to Lexingtoncar
6h 57m$121–641Bus to Memphis, fly to Blue Grass Airport
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Blue Grass Airport (LEX)plane MEM - LEX
9h 56m$127–575Bus, drive
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
16h 11m$117–228
Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX) flights
Questions & Answers
The cheapest way to get from Tupelo to Lexington is to drive which costs $75 - $110 and takes 8h.
The fastest way to get from Tupelo to Lexington is to drive and fly which takes 6h 56m and costs $65 - $370.
The distance between Tupelo and Lexington is 467 miles. The road distance is 414.5 miles.
It takes approximately 6h 56m to get from Tupelo to Lexington, including transfers.
Lexington is 1h ahead of Tupelo. It is currently 10:08 AM in Tupelo and 11:08 AM in Lexington.
Yes, the driving distance between Tupelo to Lexington is 414 miles. It takes approximately 8h to drive from Tupelo to Lexington.
There are 140+ hotels available in Lexington.
What companies run services between Tupelo, MS, USA and Lexington, KY, USA?
There is no direct connection from Tupelo to Lexington. However, you can drive to Golden Triangle Regional Airport (GTR) airport, fly to Blue Grass Airport (LEX), walk to Terminal @ Bluegrass Field, take the line 8 bus to Transit Center, then take the line 3 bus to Centre Parkway @ 1349. Alternatively, you can take a vehicle from Tupelo to Lexington via Tupelo, Memphis Bus Station, Nashville Bus Station, Fulton Station Outbound, Walmart Station Outbound, Tornado Bus Co - Nashville, La Tropicana - Louisville, KY, Preston @ Vim, S 5th @ W Jefferson, and Middletown Station @ Target in around 15h 20m.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $55–350
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville, Atlanta
- Ave. Duration
- 7h 49m
- When
- Every day
- Estimated price
- $95–550
Flights from Tupelo Regional Airport to Covington via Nashville, Atlanta
- Ave. Duration
- 7h 54m
- When
- Every day
- Estimated price
- $130–750
Flights from Memphis to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $85–500
Flights from Memphis to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $100–480
Flights from Tupelo Regional Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $130–700
Flights from Tupelo Regional Airport to Covington via Dallas/Ft.Worth
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $180–900
Flights from Memphis to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $95–550
Flights from Memphis to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville
- Ave. Duration
- 7h 15m
- When
- Monday to Saturday
- Estimated price
- $110–480
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville, Chicago Midway
- Ave. Duration
- 13h 20m
- When
- Saturday
- Estimated price
- $100–600
Flights from Tupelo Regional Airport to Covington via Nashville
- Ave. Duration
- 5h 20m
- When
- Saturday
- Estimated price
- $90–600
Flights from Tupelo Regional Airport to Covington via Nashville, Chicago Midway
- Ave. Duration
- 10h 55m
- When
- Saturday
- Estimated price
- $130–750
- Website
- united.com
Flights from Memphis to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Nashville Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 4 times a day
- Estimated price
- $35–85
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KY
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a week
- Estimated price
- $50–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $50–150
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
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