There are 7 ways to get from Tupelo to Lexington by car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly to Blue Grass Airport
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX)plane GTR - LEX
7h 55m$68–368Bus, drive via Brentwood
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Nashville Bus Stationbus
- Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
15h 20m$134–285Drive 412.1 mi
- Drive from Tupelo to Lexingtoncar 412.1 mi
8h$76–109Fly Tupelo Regional Airport to Louisville International Airport, drive
- Fly from Tupelo Regional Airport (TUP) to Louisville International Airport (SDF)plane TUP - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
6h 55m$150–530Fly Tupelo Regional Airport to Covington, drive
- Fly from Tupelo Regional Airport (TUP) to Covington (CVG)plane TUP - CVG
- Drive from Covington (CVG) to Lexingtoncar
6h 52m$131–691Bus to Memphis, fly to Blue Grass Airport
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Blue Grass Airport (LEX)plane MEM - LEX
10h 1m$122–540Bus, drive
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
16h 11m$112–183
Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX) flights
Questions & Answers
The cheapest way to get from Tupelo to Lexington is to drive which costs $75 - $110 and takes 8h.
The fastest way to get from Tupelo to Lexington is to fly and drive which takes 6h 52m and costs $130 - $700.
The distance between Tupelo and Lexington is 467 miles. The road distance is 414.5 miles.
It takes approximately 7h 55m to get from Tupelo to Lexington, including transfers.
Lexington is 1h ahead of Tupelo. It is currently 5:43 PM in Tupelo and 6:43 PM in Lexington.
Yes, the driving distance between Tupelo to Lexington is 414 miles. It takes approximately 8h to drive from Tupelo to Lexington.
There are 138+ hotels available in Lexington.
What companies run services between Tupelo, MS, USA and Lexington, KY, USA?
There is no direct connection from Tupelo to Lexington. However, you can drive to Golden Triangle Regional Airport (GTR) airport, fly to Blue Grass Airport (LEX), walk to Terminal @ Bluegrass Field, take the line 8 bus to Transit Center, then take the line 3 bus to Centre Parkway @ 1349. Alternatively, you can take a vehicle from Tupelo to Lexington via Tupelo, Memphis Bus Station, Nashville Bus Station, Fulton Station Outbound, Walmart Station Outbound, Tornado Bus Co - Nashville, La Tropicana - Louisville, KY, Preston @ Vim, S 5th @ W Jefferson, and Middletown Station @ Target in around 15h 20m.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $55–350
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville, Atlanta
- Ave. Duration
- 7h 53m
- When
- Every day
- Estimated price
- $100–550
Flights from Tupelo Regional Airport to Covington via Nashville, Atlanta
- Ave. Duration
- 6h 57m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–750
Flights from Memphis to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $90–500
Flights from Memphis to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $100–470
Flights from Tupelo Regional Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 15m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $140–700
Flights from Tupelo Regional Airport to Covington via Dallas/Ft.Worth
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $200–950
Flights from Memphis to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $100–550
Flights from Memphis to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Monday and Wednesday
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville
- Ave. Duration
- 7h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–490
Flights from Tupelo Regional Airport to Covington via Nashville
- Ave. Duration
- 5h 15m
- When
- Saturday
- Estimated price
- $100–650
Flights from Tupelo Regional Airport to Covington via Nashville, Chicago Midway
- Ave. Duration
- 10h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $140–800
- Website
- united.com
Flights from Memphis to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $19–25
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Nashville Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 4 times a day
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KY
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a week
- Estimated price
- $50–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $50–150
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
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