There are 5 ways to get from Tupelo to Lexington by car, plane, bus (Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly to Blue Grass Airport
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX)plane GTR - LEX
7h 20m$143–768Drive 412.1 mi
cheapest- Drive from Tupelo to Lexingtoncar 412.1 mi
8h$76–109Bus
- Take the bus from Tupelo to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Bus Station to Lexington Bus Stopbus Greyhound US0110
14h 26m$138–251Fly Tupelo Regional Airport to Louisville International Airport, drive
- Fly from Tupelo Regional Airport (TUP) to Louisville International Airport (SDF)plane TUP - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
4h 58m$179–638Bus to Memphis, fly to Blue Grass Airport
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Blue Grass Airport (LEX)plane MEM - LEX
9h 45m$219–1,147
Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX) flights
Questions & Answers
The cheapest way to get from Tupelo to Lexington is to drive which costs $75 - $110 and takes 8h.
The fastest way to get from Tupelo to Lexington is to fly and drive which takes 4h 58m and costs $170 - $650.
No, there is no direct bus from Tupelo to Lexington. However, there are services departing from Tupelo and arriving at Lexington Bus Stop via Atlanta Bus Station. The journey, including transfers, takes approximately 14h 26m.
The distance between Tupelo and Lexington is 467 miles. The road distance is 414.5 miles.
The best way to get from Tupelo to Lexington without a car is to bus which takes 14h 26m and costs $130 - $260.
It takes approximately 7h 20m to get from Tupelo to Lexington, including transfers.
Tupelo to Lexington bus services, operated by Greyhound-us, depart from Tupelo station.
Tupelo to Lexington bus services, operated by Greyhound-us, arrive at Atlanta Bus Station.
Lexington is 1h ahead of Tupelo. It is currently 3:15 AM in Tupelo and 4:15 AM in Lexington.
Yes, the driving distance between Tupelo to Lexington is 414 miles. It takes approximately 8h to drive from Tupelo to Lexington.
What companies run services between Tupelo, MS, USA and Lexington, KY, USA?
You can take a vehicle from Tupelo to Lexington via Tupelo, Atlanta Bus Station, and Lexington Bus Stop in around 14h 26m.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $130–750
Flights from Memphis to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Memphis to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,200
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Tupelo Regional Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 10m
- When
- Sunday
- Estimated price
- $150–700
Flights from Memphis to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 46m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $220–1,100
Flights from Memphis to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $230–1,200
- Website
- united.com
Flights from Memphis to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $230–1,200
- Website
- southwest.com
Flights from Tupelo Regional Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 37m
- When
- Saturday and Sunday
- Estimated price
- $150–600
- Website
- allegiantair.com
Flights from Memphis to Blue Grass Airport via Orlando Sanford
- Ave. Duration
- 6h 5m
- When
- Thursday
- Estimated price
- $330–1,500
- Website
- greyhound.com
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Atlanta Bus Station to Lexington Bus Stop
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Lexington Bus Stop
- Ave. Duration
- 7h 55m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–30
- Website
- https://www.greyhound.com/
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