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How to get fromTupelo to Charlotteby car, plane, bus (Greyhound, Flixbus) or bus

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There are 8 ways to get from Tupelo to Charlotte by car, plane, bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Northwest Alabama Regional Airport, fly

    best
    1. Drive from Tupelo to Northwest Alabama Regional Airport (MSL)car car
    2. Fly from Northwest Alabama Regional Airport (MSL) to Charlotte Douglas International Airport (CLT)plane plane MSL - CLT
    4h 10m
    $108–405

  2. Fly from Tupelo Regional Airport

    cheapest
    1. Fly from Tupelo Regional Airport (TUP) to Charlotte Douglas International Airport (CLT)plane plane TUP - CLT
    4h 22m
    $74–372

  3. Bus via Atlanta

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus Greyhound US0610
    2. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus FlixBus N2470
    10h 53m
    $88–155

  4. Drive 516.8 mi

    1. Drive from Tupelo to Charlottecar car 516.8 mi
    8h 50m
    $95–137

  5. Drive to Birmingham–Shuttlesworth International Airport, fly

    1. Drive from Tupelo to Birmingham-Airport-BHMcar car
    2. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Charlotte Douglas International Airport (CLT)plane plane BHM - CLT
    4h 43m
    $122–688

  6. Drive to Huntsville International Airport-Carl T Jones Field, fly

    1. Drive from Tupelo to Huntsville International Airport-Carl T Jones Field (HSV)car car
    2. Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Charlotte Douglas International Airport (CLT)plane plane HSV - CLT
    4h 53m
    $86–436

  7. Bus to Memphis, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Charlotte Douglas International Airport (CLT)plane plane MEM - CLT
    6h 34m
    $213–414

  8. Bus

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus Greyhound US0610
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus Greyhound US0670
    10h 54m
    $90–162

Northwest Alabama Regional Airport (MSL) to Charlotte Douglas International Airport (CLT) flights

Calendar12Weekly Planes
Duration1h 35mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

What companies run services between Tupelo, MS, USA and Charlotte, NC, USA?

You can take a vehicle from Tupelo to Charlotte Bus Station via Tupelo, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 10h 53m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and American Airlines fly from Tupelo Regional Airport (TUP) to Charlotte Douglas International Airport (CLT) twice daily.

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