There are 7 ways to get from Topeka to Tupelo by bus (Greyhound, Flixbus), train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via St. Louis
best- Take the bus from Topeka to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
15h 34m$109–203Train, bus
- Take the train from Topeka Station to Kansas Citytrain
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
18h$158–330Drive 599.8 mi
- Drive from Topeka to Tupelocar 599.8 mi
10h 48m$110–159Drive to Manhattan Regional Airport, fly to Golden Triangle Regional Airport, drive
- Drive from Topeka to Manhattan Regional Airport (MHK)car
- Fly from Manhattan Regional Airport (MHK) to Golden Triangle Regional Airport (GTR)plane MHK - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
11h 27m$113–474Bus
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Take the bus from Kansas City to Tulsabus
- Take the bus from Tulsa to Memphisbus
- Take the bus from Memphis Bus Station to Tupelobus
19h 53m$228–335Drive to Manhattan Regional Airport, fly to Tupelo Regional Airport
- Drive from Topeka to Manhattan Regional Airport (MHK)car
- Fly from Manhattan Regional Airport (MHK) to Tupelo Regional Airport (TUP)plane MHK - TUP
8h 15m$136–585Bus to Kansas City, fly to Golden Triangle Regional Airport, drive
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Fly from Kansas City (MCI) to Golden Triangle Regional Airport (GTR)plane MCI - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
9h 15m$174–671
Manhattan Regional Airport (MHK) to Golden Triangle Regional Airport (GTR) flights
Questions & Answers
The cheapest way to get from Topeka to Tupelo is to bus via St. Louis which costs $100 - $210 and takes 15h 34m.
The fastest way to get from Topeka to Tupelo is to drive and fly which takes 8h 15m and costs $130 - $600.
No, there is no direct bus from Topeka to Tupelo. However, there are services departing from Topeka and arriving at Tupelo via St Louis Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 15h 34m.
The distance between Topeka and Tupelo is 710 miles. The road distance is 603.3 miles.
The best way to get from Topeka to Tupelo without a car is to bus via St. Louis which takes 15h 34m and costs $100 - $210.
It takes approximately 15h 34m to get from Topeka to Tupelo, including transfers.
Topeka to Tupelo bus services, operated by Greyhound USA, depart from Topeka station.
Topeka to Tupelo bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Topeka to Tupelo is 603 miles. It takes approximately 10h 48m to drive from Topeka to Tupelo.
Book your Topeka to Tupelo bus tickets online with Omio.
What companies run services between Topeka, KS, USA and Tupelo, MS, USA?
You can take a bus from Topeka to Tupelo via St Louis Bus Station, Memphis Bus Station, and Tupelo in around 15h 34m.
- Website
- contouraviation.com
Flights from Manhattan Regional Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 42m
- When
- Every day
- Estimated price
- $270–1,200
Flights from Manhattan Regional Airport to Tupelo Regional Airport via Chicago O'Hare, Nashville
- Ave. Duration
- 10h 15m
- When
- Sunday
- Estimated price
- $110–550
Flights from Manhattan Regional Airport to Tupelo Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 10h 15m
- When
- Monday to Saturday
- Estimated price
- $170–750
Flights from Manhattan Regional Airport to Tupelo Regional Airport via Dallas/Ft.Worth, Nashville
- Ave. Duration
- 12h 45m
- When
- Sunday
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Topeka Station to Kansas City
- Ave. Duration
- 2h 1m
- Frequency
- Once daily
- Estimated price
- $18–40
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $75–170
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Topeka to St Louis Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Twice daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $14–27
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $14–27
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $14–27
- Website
- Greyhound
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More Questions & Answers
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