Rome2Rio

How to get fromKey West to Tupeloby plane, car, shuttle, bus, bus (Greyhound) or train

Find Transport to Tupelo

See all options

There are 7 ways to get from Key West to Tupelo by plane, car, shuttle, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Key West International Airport (EYW) to Golden Triangle Regional Airport (GTR)planeEYW - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
    7h 21m
    $108–471
  2. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle
    2. Take the bus from Miami Airport to Orlando - RedCoach Station, FLbus
    3. Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus
    4. Take the bus from Atlanta Bus Station to Tupelobus
    25h
    $289–549
  3. Drive 1,009 mi

    1. Drive from Key West to Tupelocar1,009 mi
    18h 53m
    $185–266
  4. Fly to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Key West International Airport (EYW) to Birmingham–Shuttlesworth International Airport (BHM)planeEYW - BHM
    2. Drive from Birmingham-Airport-BHM to Tupelocar
    6h 23m
    $166–754
  5. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Key West International Airport (EYW) to Huntsville International Airport-Carl T Jones Field (HSV)planeEYW - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar
    7h 13m
    $145–649
  6. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30busLks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus
    4. Take the bus from Atlanta Bus Station to Tupelobus
    26h 40m
    $167–381
  7. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30busLks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus
    3. Take the train from Miami Amtrak Station to Savannah Stationtrain
    4. Take the bus from Savannah Bus Station to Atlanta Bus Stationbus
    5. Take the bus from Atlanta Bus Station to Tupelobus
    30h 18m
    $269–640

Key West International Airport (EYW) to Golden Triangle Regional Airport (GTR) flights

Calendar28Weekly Planes
Duration8h 36mAverage Duration
Ticket$88Cheapest Price
See schedules

Questions & Answers

What companies run services between Key West, FL, USA and Tupelo, MS, USA?

You can take a bus from N Roosevelt & 3rd Street to Tupelo via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, and Tupelo in around 26h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound