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How to get fromBuffalo to Tupeloby plane, car, bus (Greyhound), train or bus

Find Transport to Tupelo

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There are 8 ways to get from Buffalo to Tupelo by plane, car, bus (Greyhound), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Golden Triangle Regional Airport (GTR)planeBUF - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
    10h 2m
    $155–847

  2. Bus via Reading

    1. Take the bus from Buffalo, NY to Cincinnati, OHbus
    2. Take the bus from Cincinnati Bus Station to Nashville Bus Stationbus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus
    4. Take the bus from Memphis Bus Station to Tupelobus
    23h 54m
    $162–382

  3. Train, bus via St. Louis

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to St. Louistrain
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus
    4. Take the bus from Memphis Bus Station to Tupelobus
    26h 50m
    $196–722

  4. Drive 898 mi

    1. Drive from Buffalo to Tupelocar898 mi
    16h 11m
    $164–237

  5. Fly to Tupelo Regional Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Tupelo Regional Airport (TUP)planeBUF - TUP
    8h 28m
    $200–1,100

  6. Fly to Memphis, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Memphis (MEM)planeBUF - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus
    9h 38m
    $227–1,258

  7. Train, bus

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain
    2. Take the bus from Chicago Bus Station to Memphis Bus Stationbus
    3. Take the bus from Memphis Bus Station to Tupelobus
    25h 13m
    $176–592

  8. Bus (Greyhound)

    1. Take the bus from Buffalo to Cleveland Bus Stationbus
    2. Take the bus from Cleveland Bus Station to Nashville Bus Stationbus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus
    4. Take the bus from Memphis Bus Station to Tupelobus
    26h 14m
    $190–415

Buffalo Niagara International Airport (BUF) to Golden Triangle Regional Airport (GTR) flights

Calendar25Weekly Planes
Duration8h 35mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Tupelo, MS, USA?

You can take a bus from Buffalo, NY to Tupelo via Cincinnati, OH, Cincinnati Bus Station, Nashville Bus Station, Memphis Bus Station, and Tupelo in around 23h 54m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Tupelo Regional Airport (TUP) twice daily.

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