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How to get fromBuffalo to Tupeloby plane, car, bus (Greyhound, Flixbus), train, or bus

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There are 8 ways to get from Buffalo to Tupelo by plane, car, bus (Greyhound, Flixbus), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Golden Triangle Regional Airport (GTR)plane plane BUF - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    8h 49m
    $137–645

  2. Fly to Tupelo Regional Airport

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Tupelo Regional Airport (TUP)plane plane BUF - TUP
    7h 58m
    $120–596

  3. Bus via Reading

    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus
    2. Take the bus from Cincinnati Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    23h 49m
    $141–283

  4. Train, bus via St. Louis

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    26h 55m
    $313–804

  5. Drive 898.1 mi

    1. Drive from Buffalo to Tupelocar car 898.1 mi
    16h 18m
    $164–237

  6. Fly to Memphis, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Memphis (MEM)plane plane BUF - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    9h 17m
    $223–1,072

  7. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    24h 49m
    $166–320

  8. Train, bus

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    25h 8m
    $268–689

Buffalo Niagara International Airport (BUF) to Golden Triangle Regional Airport (GTR) flights

Calendar35Weekly Planes
Duration7h 54mAverage Duration
Ticket$125Cheapest Price
See schedules

Questions & Answers

Map of how to get from Buffalo to Tupelo.ExpandLaunch map view
  • Distance: 917.3 mi
  • Duration: 8h 49m

What companies run services between Buffalo, NY, USA and Tupelo, MS, USA?

You can take a bus from Buffalo, NY to Tupelo via Cincinnati, OH, Cincinnati Bus Station, Nashville Bus Station, Memphis Bus Station, and Tupelo in around 23h 49m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Tupelo Regional Airport (TUP) 4 times a day.

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