There are 6 ways to get from Rochester to Lexington by plane, car, train, bus, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to Louisville International Airport, drive
best- Fly from Rochester (ROC) to Louisville International Airport (SDF)ROC - SDF
- Drive from Louisville-Airport-SDF to Lexington
5h 37m$151–741Bus
cheapest- Take the bus from Rochester Bus Stop to Buffalo
- Take the bus from Buffalo, NY to Cincinnati, OH
- Take the bus from Cincinnati Bus Station to Lexington Bus Stop
15h 22m$106–199Train, bus
- Take the train from Rochester to ToledoLake Shore Limited
- Take the bus from Toledo Bus Stop to Lexington Bus StopGreyhound US0110
15h 1m$107–278Drive 586.9 mi
- Drive from Rochester to Lexington586.9 mi
9h 59m$108–155Fly Rochester to Blue Grass Airport
- Fly from Rochester (ROC) to Blue Grass Airport (LEX)ROC - LEX
6h 26m$209–1,122Bus to Buffalo Niagara International Airport, fly to Blue Grass Airport
- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX)BUF - LEX
8h 23m$247–1,423
Rochester (ROC) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Rochester to Lexington is to drive which costs $100 - $160 and takes 9h 59m.
The fastest way to get from Rochester to Lexington is to fly and drive which takes 5h 37m and costs $150 - $750.
The distance between Rochester and Lexington is 631 miles. The road distance is 590.4 miles.
The best way to get from Rochester to Lexington without a car is to train and bus which takes 15h 1m and costs $100 - $280.
It takes approximately 5h 37m to get from Rochester to Lexington, including transfers.
The best way to get from Rochester to Lexington is to fly which takes 6h 26m and costs $200 - $1,200. Alternatively, you can bus, which costs $100 - $200 and takes 15h 22m.
Yes, the driving distance between Rochester to Lexington is 590 miles. It takes approximately 9h 59m to drive from Rochester to Lexington.
There are 143+ hotels available in Lexington.
What companies run services between Rochester, NY, USA and Lexington, KY, USA?
Delta, American Airlines, and United Airlines fly from Rochester (ROC) to Blue Grass Airport (LEX) every 3 hours. Alternatively, you can take a bus from Rochester Bus Stop to Lexington via Buffalo, Buffalo, NY, Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 15h 22m.
- Website
- aa.com
Flights from Rochester to Louisville International Airport via Reagan Washington
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $130–750
Flights from Rochester to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $150–800
Flights from Rochester to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $240–1,300
Flights from Rochester to Blue Grass Airport via Philadelphia
- Ave. Duration
- 5h 23m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $220–1,200
Flights from Rochester to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,300
Flights from Buffalo Niagara International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $290–1,600
Flights from Buffalo Niagara International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $280–1,500
Flights from Buffalo Niagara International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $280–1,500
- Website
- delta.com
Flights from Rochester to Louisville International Airport via Detroit
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $120–700
Flights from Rochester to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Rochester to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 4h 44m
- When
- Sunday
- Estimated price
- $240–1,300
Flights from Rochester to Blue Grass Airport via Atlanta
- Ave. Duration
- 6h 5m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $270–1,400
Flights from Buffalo Niagara International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $230–1,400
Flights from Buffalo Niagara International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $330–1,700
Flights from Buffalo Niagara International Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 5h 44m
- When
- Sunday
- Estimated price
- $300–1,600
- Website
- united.com
Flights from Rochester to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $130–750
Flights from Rochester to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Buffalo Niagara International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $280–1,500
- Website
- southwest.com
Flights from Rochester to Louisville International Airport via Baltimore
- Ave. Duration
- 5h 43m
- When
- Monday, Saturday, and Sunday
- Estimated price
- $140–750
Flights from Rochester to Louisville International Airport via Chicago Midway
- Ave. Duration
- 5h 10m
- When
- Monday, Friday, and Sunday
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Rochester to Toledo
- Ave. Duration
- 6h 44m
- Frequency
- Twice daily
- Estimated price
- $35–160
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Toledo Bus Stop to Lexington Bus Stop
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $16–23
- Website
- https://www.greyhound.com/
Bus from Cincinnati Bus Station to Lexington Bus Stop
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $19–50
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $15–21
- Schedules at
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $15–21
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Buffalo, NY to Cincinnati, OH
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://baronsbus.com
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