• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
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  • Airbnb
  • Expedia

There are 6 ways to get from Wilmington to Lexington by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Philadelphia, fly  •  4 h 14 min

  1. Take the train from Wilmington Amtrak Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Lexington (LEX) PHL - LEX

$281 - $988

Cheapest option

Train, bus Greyhound USA  •  20 h 58 min

  1. Take the train from Wilmington to University City
  2. Take the bus from Philadelphia, Pa to Dayton Trotwood, Oh
  3. Take the bus from Dayton Trotwood, Oh to Cincinnati, Oh
  4. Take the bus from Cincinnati, Oh to Lexington, Ky

$120 - $260

4 alternative options

Train to Reagan Washington, fly  •  4 h 55 min

  1. Take the train from Wilmington Amtrak Station to Washington Union Station
  2. Fly from Reagan Washington (DCA) to Lexington (LEX) DCA - LEX

$259 - $818

Train, bus SkyHorse / Jaguar  •  15 h 38 min

  1. Take the train from Wilmington Amtrak Station to New York Penn Station Acela Express / ...
  2. Take the bus from New York, NY to Lexington, KY

$188 - $336

Train Amtrak, bus  •  27 h 43 min

  1. Take the train from Wilmington Amtrak Station to Indianapolis Amtrak Station
  2. Take the bus from Indianapolis, IN to Cincinnati, OH
  3. Take the bus from Cincinnati, Oh to Lexington, Ky

$172 - $424

Drive  •  10 h 8 min

  1. Drive from Wilmington to Lexington 611.9 miles

$60 - $90

Questions & Answers

The cheapest way to get from Wilmington to Lexington is to drive which costs $60 - $90 and takes 10 h 8 min.

More details

The quickest way to get from Wilmington to Lexington is to train and fly which costs $280 - $1,000 and takes 4 h 14 min.

More details

The distance between Wilmington and Lexington is 498 miles. The road distance is 611.9 miles.

Get driving directions

The best way to get from Wilmington to Lexington without a car is to train and bus which takes 15 h 38 min and costs $180 - $340.

More details

It takes approximately 4 h 14 min to get from Wilmington to Lexington, including transfers.

More details

The quickest flight from Philadelphia Airport to Lexington Airport is the direct flight which takes 2 h 1 min.

Search flights

Yes, the driving distance between Wilmington to Lexington is 612 miles. It takes approximately 10 h 8 min to drive from Wilmington to Lexington.

Get driving directions

United Airlines, Delta and American Airlines offer flights from Philadelphia Airport to Lexington Airport.

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There are 76+ hotels available in Lexington. Prices start at $59 USD per night.

More details

Map of how to get from Wilmington to Lexington.
Launch map view
  • Distance: 498.2 miles
  • Duration: 4 h 14 min

What companies run services between Wilmington, DE, USA and Lexington, KY, USA?

There is no direct connection from Wilmington to Lexington. However, you can take the train to Philadelphia 30th Street Station, take the walk to 30th Street Station, take the train to Airport Terminal A, take the walk to Philadelphia airport, fly to Lexington, then take the taxi to Lexington. Alternatively, you can take the train to Washington Union Station, take the walk to UNION STATION station, take the subway to GALLERY PLACE CHINATOWN station, take the subway to NATIONAL AIRPORT station, take the walk to Reagan Washington airport, fly to Lexington, then take the taxi to Lexington.

Airlines
Delta
Website
delta.com
Flights from Philadelphia to Lexington via Detroit
Ave. Duration
4 h 28 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$320 - $900
Flights from Philadelphia to Lexington via Atlanta
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$320 - $900
Flights from Reagan Washington to Lexington
Ave. Duration
1 h 48 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $600
Flights from Reagan Washington to Lexington via Atlanta
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$270 - $600
Flights from Reagan Washington to Lexington via Detroit
Ave. Duration
4 h 17 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $600
American Airlines
Website
aa.com
Flights from Philadelphia to Lexington
Ave. Duration
2 h 3 min
When
Every day
Estimated price
$360 - $800
Flights from Philadelphia to Lexington via Charlotte
Ave. Duration
4 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$360 - $800
Flights from Philadelphia to Lexington via Chicago O'Hare
Ave. Duration
4 h 46 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$360 - $800
Flights from Reagan Washington to Lexington via Charlotte
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$290 - $650
Flights from Reagan Washington to Lexington via Philadelphia
Ave. Duration
4 h 7 min
When
Sunday
Estimated price
$290 - $650
United Airlines
Website
united.com
Flights from Philadelphia to Lexington via Chicago O'Hare
Ave. Duration
4 h 38 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$370 - $1,400
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Wilmington Amtrak Station to Philadelphia 30th Street Station
Ave. Duration
19 min
Frequency
Hourly
Estimated price
$50 - $150
Website
amtrak.com
Business Seat
$50 - $140
First Class Seat
$110 - $150
Train from Wilmington Amtrak Station to Washington Union Station
Ave. Duration
1 h 24 min
Frequency
Hourly
Estimated price
$80 - $230
Website
amtrak.com
Business Seat
$80 - $190
First Class Seat
$160 - $230
Train from Wilmington Amtrak Station to New York Penn Station
Ave. Duration
1 h 31 min
Frequency
Hourly
Estimated price
$85 - $230
Website
amtrak.com
Business Seat
$85 - $190
First Class Seat
$160 - $230
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Wilmington Amtrak Station to Indianapolis Amtrak Station
Ave. Duration
20 h 31 min
Frequency
3 times a week
Estimated price
$110 - $330
Website
amtrak.com
Coach Seat
$110 - $170
Flexi Coach Seat
$200 - $290
Business Coach Seat
$230 - $330
Room
$460 - $650
Bus operators
SkyHorse / Jaguar
Phone
+1 917.288.6888
Email
vaseagull@gotobus.com
Website
skyhorsebus.com
Bus from New York, NY to Lexington, KY
Ave. Duration
12 h 30 min
Frequency
Once daily
Estimated price
$70
Schedules at
gotobus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Philadelphia, Pa to Dayton Trotwood, Oh
Ave. Duration
13 h 55 min
Frequency
4 times a day
Estimated price
$55 - $150
Website
greyhound.com
Economy
$55 - $95
Flexible
$110 - $150
Bus from Dayton Trotwood, Oh to Cincinnati, Oh
Ave. Duration
1 h 20 min
Frequency
5 times a day
Estimated price
$12 - $27
Website
greyhound.com
Economy
$12 - $18
Flexible
$21 - $27
Bus from Cincinnati, Oh to Lexington, Ky
Ave. Duration
1 h 25 min
Frequency
4 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.