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How to get fromPresque Isle to Chicagoby plane, train, bus, bus (Amtrak, Flixbus) or car

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There are 8 ways to get from Presque Isle to Chicago by plane, train, bus, bus (Amtrak, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Presque Isle to General Mitchell International Airport, train

    best
    1. Fly from Presque Isle (PQI) to General Mitchell International Airport (MKE)plane plane PQI - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    13h 59m
    $228–1,068

  2. Fly Presque Isle to Chicago O'Hare International Airport

    cheapest
    1. Fly from Presque Isle (PQI) to Chicago O'Hare International Airport (ORD)plane plane PQI - ORD
    6h 21m
    $79–364

  3. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the train from Boston to Chicago Union Stationtrain train
    32h 8m
    $286–651

  4. Bus

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to New York Midtownbus bus
    4. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    35h 26m
    $201–346

  5. Drive 1,221.1 mi

    1. Drive from Presque Isle to Chicagocar car 1,221.1 mi
    22h 10m
    $223–322

  6. Bus to Bangor, fly to Chicago O'Hare International Airport

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Fly from Bangor (BGR) to Chicago O'Hare International Airport (ORD)plane plane BGR - ORD
    8h 55m
    $105–438

  7. Fly Presque Isle to Chicago Midway International Airport

    1. Fly from Presque Isle (PQI) to Chicago Midway International Airport (MDW)plane plane PQI - MDW
    8h 25m
    $129–614

  8. Bus to Fredericton International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Perth Andover to Frederictonbus bus
    2. Fly from Fredericton International Airport (YFC) to Chicago O'Hare International Airport (ORD)plane plane YFC - ORD
    11h 44m
    $513–1,551

Presque Isle to Chicago by bus and train

Calendar7Weekly Services
Duration32h 8mAverage Duration
Ticket$286Cheapest Price
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Questions & Answers

What companies run services between Presque Isle, ME, USA and Chicago, IL, USA?

You can take a bus from Presque Isle, Maine to Chicago Bus Station via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, and New York Midtown in around 35h 26m. Alternatively, JetBlue Airways, Southwest Airlines, and two other airlines fly from Presque Isle (PQI) to Chicago Midway International Airport (MDW) twice daily.

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