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How to get fromPresque Isle to Chicagoby plane, train, bus, bus (Amtrak, Flixbus) or car

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There are 8 ways to get from Presque Isle to Chicago by plane, train, bus, bus (Amtrak, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Presque Isle to General Mitchell International Airport, train

    best
    1. Fly from Presque Isle (PQI) to General Mitchell International Airport (MKE)planePQI - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain
    10h 40m
    $221–1,079

  2. Fly Presque Isle to Chicago O'Hare International Airport

    cheapest
    1. Fly from Presque Isle (PQI) to Chicago O'Hare International Airport (ORD)planePQI - ORD
    7h 2m
    $84–394

  3. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus
    3. Take the train from Boston to Chicago Union Stationtrain
    32h 8m
    $206–851

  4. Bus

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus
    3. Take the bus from Boston to New York Midtownbus
    4. Take the bus from New York Midtown to Chicago Bus Stationbus
    35h 33m
    $191–381

  5. Drive 1,221.1 mi

    1. Drive from Presque Isle to Chicagocar1,221.1 mi
    22h 4m
    $223–322

  6. Bus to Bangor, fly to Chicago O'Hare International Airport

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus
    2. Fly from Bangor (BGR) to Chicago O'Hare International Airport (ORD)planeBGR - ORD
    8h 54m
    $100–388

  7. Fly Presque Isle to Chicago Midway International Airport

    1. Fly from Presque Isle (PQI) to Chicago Midway International Airport (MDW)planePQI - MDW
    7h 10m
    $109–514

  8. Bus to Fredericton International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Perth Andover to Frederictonbus
    2. Fly from Fredericton International Airport (YFC) to Chicago O'Hare International Airport (ORD)planeYFC - ORD
    11h 44m
    $128–521

Presque Isle to Chicago by bus and train

Calendar7Weekly Services
Duration32h 8mAverage Duration
Ticket$206Cheapest Price
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Questions & Answers

What companies run services between Presque Isle, ME, USA and Chicago, IL, USA?

You can take a bus from Presque Isle, Maine to Chicago Bus Station via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, and New York Midtown in around 35h 33m. Alternatively, JetBlue Airways, Delta, and two other airlines fly from Presque Isle (PQI) to Chicago O'Hare International Airport (ORD) once daily.

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