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How to get fromPresque Isle to Chicagoby bus, plane, bus (Amtrak, Flixbus), train, car, or bus (Amtrak, Greyhound)

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There are 9 ways to get from Presque Isle to Chicago by bus, plane, bus (Amtrak, Flixbus), train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Bangor, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Fly from Bangor (BGR) to Chicago O'Hare International Airport (ORD)plane plane BGR - ORD
    8h 49m
    $130–588

  2. Fly Presque Isle to Chicago O'Hare International Airport

    cheapest
    1. Fly from Presque Isle (PQI) to Chicago O'Hare International Airport (ORD)plane plane PQI - ORD
    6h 13m
    $109–504

  3. Bus

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to New York Midtownbus bus
    4. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    31h 52m
    $204–351

  4. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the train from Boston to Chicago Union Stationtrain train
    32h 8m
    $346–751

  5. Drive 1,221.6 mi

    1. Drive from Presque Isle to Chicagocar car 1,221.6 mi
    22h 11m
    $223–322

  6. Fly Presque Isle to Chicago Midway International Airport

    1. Fly from Presque Isle (PQI) to Chicago Midway International Airport (MDW)plane plane PQI - MDW
    7h
    $129–614

  7. Bus to Fredericton International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Perth Andover to Frederictonbus bus
    2. Fly from Fredericton International Airport (YFC) to Chicago O'Hare International Airport (ORD)plane plane YFC - ORD
    11h 24m
    $412–1,000

  8. Fly Presque Isle to General Mitchell International Airport, train

    1. Fly from Presque Isle (PQI) to General Mitchell International Airport (MKE)plane plane PQI - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    9h 12m
    $232–1,028

  9. Bus via Brook Park

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    32h 16m
    $231–421

Presque Isle to Chicago by bus

Calendar7Weekly Buses
Duration31h 52mAverage Duration
Ticket$204Cheapest Price
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Questions & Answers

What companies run services between Presque Isle, ME, USA and Chicago, IL, USA?

You can take a bus from Presque Isle, Maine to Chicago Bus Station via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, and New York Midtown in around 31h 52m. Alternatively, JetBlue Airways and Southwest Airlines fly from Presque Isle (PQI) to Chicago Midway International Airport (MDW) twice a week.

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